Somatotropin

Generic Name
Somatotropin
Brand Names
Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
Drug Type
Biotech
Chemical Formula
-
CAS Number
12629-01-5
Unique Ingredient Identifier
NQX9KB6PCL
Background

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...

Indication

Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...

Associated Conditions
Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
Associated Therapies
-

Growth Hormone Adding to Controlled Ovarian Hyperstimulation for Improving Embryo Quality

Not Applicable
Conditions
Interventions
First Posted Date
2019-05-29
Last Posted Date
2022-01-11
Lead Sponsor
Reproductive & Genetic Hospital of CITIC-Xiangya
Target Recruit Count
128
Registration Number
NCT03966339
Locations
🇨🇳

Reproductive & Genetic Hospital of CITIC-XIANGYA, Changsha, Hunan, China

Treatment of GHD Associated With CHF

First Posted Date
2018-12-14
Last Posted Date
2019-02-15
Lead Sponsor
Federico II University
Target Recruit Count
64
Registration Number
NCT03775993

Effects of Growth Hormone on Difficult Ventilator Weaning Patients

First Posted Date
2018-10-24
Last Posted Date
2019-08-21
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
60
Registration Number
NCT03717168
Locations
🇪🇬

Department of Anesthesia and Pain medicine.National Cancer Institute, Cairo, Egypt

GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-08-06
Last Posted Date
2021-01-27
Lead Sponsor
Corporacion Parc Tauli
Target Recruit Count
30
Registration Number
NCT03616509
Locations
🇪🇸

Parc Taulí Hospital Universitari, Sabadell, Barcelona, Spain

Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy

First Posted Date
2018-06-13
Last Posted Date
2024-01-19
Lead Sponsor
The University of Texas Medical Branch, Galveston
Target Recruit Count
83
Registration Number
NCT03554265
Locations
🇺🇸

University of Texas Medical Branch, Galveston, Texas, United States

Adipose Tissue and Serum Inflammation in GH Deficiency

Recruiting
Conditions
Interventions
First Posted Date
2018-04-18
Last Posted Date
2024-05-06
Lead Sponsor
Columbia University
Target Recruit Count
60
Registration Number
NCT03500913
Locations
🇺🇸

Neuroendocrine Unit and Pituitary Center, Columbia University Irving Medical Center, New York, New York, United States

Post Marketing Surveillance on Long-term Use With Norditropin® (Short Stature Due to Noonan Syndrome)

Completed
Conditions
Interventions
First Posted Date
2018-02-19
Last Posted Date
2022-11-14
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
71
Registration Number
NCT03435627
Locations
🇯🇵

Novo Nordisk Investigational Site, Tokyo, Japan

Growth Hormone Therapy in Liver Cirrhosis

First Posted Date
2018-02-05
Last Posted Date
2023-05-03
Lead Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Target Recruit Count
76
Registration Number
NCT03420144
Locations
🇮🇳

Post Graduate Institute of Medical Education and Research, Chandigarh, India

Study to Assess Long-term Effectiveness of Zomacton® and Treatment Adherence in Patients With Growth Hormone Deficiency or Ullrich-Turner Syndrome

Terminated
Conditions
Interventions
First Posted Date
2017-09-07
Last Posted Date
2018-12-13
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
4
Registration Number
NCT03274973
Locations
🇩🇪

Klinik fuer Allgemeine Paediatrie der Christian-Albrechts-Universitaet zu Kiel (there might be other sites in this country), Kiel, Germany

Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy

Recruiting
Conditions
Interventions
First Posted Date
2017-07-21
Last Posted Date
2024-05-06
Lead Sponsor
Columbia University
Target Recruit Count
12
Registration Number
NCT03225755
Locations
🇺🇸

Neuroendocrine Unit and Pituitary Center, Columbia University, New York, New York, United States

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