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Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Generic Name
Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Brand Names
Prevnar 20, Vaxneuvance
Drug Type
Biotech
Unique Ingredient Identifier
9WP2BC3I04

Overview

Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 33F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

Background

Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 33F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

FDA Approved Products

Prevnar 20
Manufacturer:Wyeth Pharmaceutical Division of Wyeth Holdings LLC
Route:INTRAMUSCULAR
Strength:2.2 ug in 0.5 mL
Approved: 2025/04/18
NDC:0005-2000

Singapore Approved Products

APEXXNAR SUSPENSION FOR INJECTION IN SINGLE-DOSE PRE-FILLED SYRINGE 0.5ML
Manufacturer:Pfizer Ireland Pharmaceuticals
Form:INJECTION, SUSPENSION
Strength:2.2 μg/0.5ml
Online:Yes
Approved: 2022/11/30
Approval:SIN16648P

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