Overview
Autologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis. It has been used since 1995 as Carticel and gained biologic license in 1997. The surgical implantation was first performed in Sweden.
Indication
in Autologous cultured chondrocytes are indicated the repair of symptomatic, single or multiple full-thickness cartilage defects of the knee with or without bone involvement in adults aged 55 years and less. They are not indicated for use in joints other than the knee.
Associated Conditions
- Articular Cartilage Defects in the Knee Joint
Clinical Trials
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No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Vericel Corporation | 69866-1025 | INTRA-ARTICULAR | 1.2e+007 1 in 1 1 | 2/6/2017 |
EMA Drug Approvals
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HSA Drug Approvals
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NMPA Drug Approvals
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PPB Drug Approvals
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TGA Drug Approvals
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Health Canada Drug Approvals
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CIMA AEMPS Drug Approvals
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Philippines FDA Drug Approvals
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Saudi SFDA Drug Approvals
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Malaysia NPRA Drug Approvals
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UK EMC Drug Information
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