Gadoteric acid

Generic Name
Gadoteric acid
Brand Names
Dotarem
Drug Type
Small Molecule
Chemical Formula
C16H25GdN4O8
CAS Number
72573-82-1
Unique Ingredient Identifier
QVF9Y6955W
Background

Gadoteric acid is a macrocycle-structured gadolinium-based MRI contrast agent. It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). As a paramagnetic molecule, gadoterate develops a magnetic moment when placed in a magnetic field. This magnetic moment enha...

Indication

Gadoteric acid is indicated for intravenous use with magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with disruption of the blood brain barrier (BBB) and/or abnormal vascularity.

Associated Conditions
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Associated Therapies
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Clinical Trials
Related News

Crossover Comparison of MultiHance and Dotarem

First Posted Date
2014-02-25
Last Posted Date
2017-01-10
Lead Sponsor
Bracco Diagnostics, Inc
Target Recruit Count
179
Registration Number
NCT02070380
Locations
🇺🇸

Samaritan Health Services, Corvallis, Oregon, United States

Efficacy Evaluation of Dotarem Compared to Gadovist in the Diagnosis of Peripheral Arterial Disease

Phase 4
Completed
Conditions
Peripheral Arterial Disease
Interventions
Drug: Gadovist
Drug: Dotarem
First Posted Date
2009-12-04
Last Posted Date
2012-12-11
Lead Sponsor
Guerbet
Target Recruit Count
189
Registration Number
NCT01026389
Locations
🇦🇹

AKH hospital, Wien, Austria

Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)

Phase 3
Completed
Conditions
Cerebral Arterial Diseases
Interventions
Drug: Dotarem
Other: TOF MRA
First Posted Date
2009-11-13
Last Posted Date
2016-06-16
Lead Sponsor
Guerbet
Target Recruit Count
211
Registration Number
NCT01012674
Locations
🇺🇸

Guerbet LLC, Bloomington, Indiana, United States

Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)

Phase 3
Completed
Conditions
Cerebral Arterial Diseases
Interventions
Drug: Dotarem
Other: TOF MRA
First Posted Date
2009-11-10
Last Posted Date
2016-06-16
Lead Sponsor
Guerbet
Target Recruit Count
222
Registration Number
NCT01010932
Locations
🇺🇸

Guerbet LLC, Bloomington, Indiana, United States

Renal Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time-Of-Flight (TOF)

Phase 3
Terminated
Conditions
Renal Disease
Interventions
Other: Time of Flight
Drug: Dotarem
First Posted Date
2009-09-21
Last Posted Date
2016-05-26
Lead Sponsor
Guerbet
Target Recruit Count
13
Registration Number
NCT00980681
Locations
🇺🇸

Guerbet LLC, Bloomington, Indiana, United States

Contrast Enhanced MRI of the CNS - Patients With Known Cerebral Neoplastic Lesions.

First Posted Date
2008-10-02
Last Posted Date
2014-12-05
Lead Sponsor
Bayer
Target Recruit Count
166
Registration Number
NCT00764387

A Clinical Study of Gadoteric Acid in Non-Coronary Magnetic Resonance (MR) Angiography

Phase 4
Completed
Conditions
Arterial Occlusive Disease
First Posted Date
2007-03-15
Last Posted Date
2008-11-26
Lead Sponsor
Guerbet
Registration Number
NCT00447889
Locations
🇰🇷

Asan Medical Center, Seoul, Korea, Republic of

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