Overview
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.
Indication
Injection, USP 40 mEq is indicated as a source of sodium, for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Sodium acetate and other bicarbonate precursors are alkalinising agents, and can be used to correct metabolic acidosis, or for alkalinisation of the urine.
Associated Conditions
- Hyponatremia
- Hypovolaemia
- Mild, moderate Metabolic Acidosis
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
---|---|---|---|---|---|
2022/04/25 | Phase 3 | Active, not recruiting |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
---|---|---|---|---|---|
Woodward Pharma Services LLC | 69784-232 | INTRAVENOUS | 328 mg in 1 mL | 11/1/2023 | |
Baxter Healthcare Company | 0338-1147 | INTRAVENOUS | 340 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Corporation | 0338-1147 | INTRAVENOUS | 340 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Company | 0338-1142 | INTRAVENOUS | 217 mg in 100 mL | 9/21/2020 | |
Baxter Healthcare Corporation | 0338-1142 | INTRAVENOUS | 217 mg in 100 mL | 9/21/2020 | |
B. Braun Medical Inc. | 0264-7730 | INTRAVENOUS | 0.32 g in 100 mL | 10/17/2022 | |
Fresenius Kabi USA, LLC | 65219-389 | INTRAVENOUS | 368 mg in 100 mL | 6/18/2021 | |
Baxter Healthcare Company | 0338-7032 | INTRAVENOUS | 340 mg in 100 mL | 4/13/2021 | |
Baxter Healthcare Corporation | 0338-7032 | INTRAVENOUS | 340 mg in 100 mL | 4/13/2021 | |
Baxter Healthcare Company | 0338-1145 | INTRAVENOUS | 297 mg in 100 mL | 9/21/2020 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
---|---|---|---|
No EMA approvals found for this drug. |
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
GELASPAN SOLUTION FOR INFUSION | SIN15336P | INFUSION, SOLUTION | 3.27g/1000ml | 10/4/2017 | |
AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION | SIN15411P | INFUSION, SOLUTION | 2.858g/1000ml | 1/23/2018 | |
SmofKabiven Peripheral Emulsion for Infusion | SIN14287P | INJECTION, EMULSION | 5.62g /1000ml | 1/8/2013 | |
OLICLINOMEL N7-1000 E EMULSION FOR INFUSION | SIN12539P | EMULSION | 2.45 g/l | 5/6/2004 | |
PLASMA-LYTE A INJECTION | SIN06523P | INJECTION | 368 mg/100 ml | 8/19/1991 | |
NUTRIFLEX® OMEGA SPECIAL EMULSION FOR INFUSION | SIN15469P | INJECTION, EMULSION | 0.250g/1000ml | 4/23/2018 | |
PERIOLIMEL N4E Emulsion for Infusion | SIN16888P | EMULSION | 1.16g/L | 10/20/2023 | |
NUTRIFLEX® OMEGA SPECIAL B. BRAUN EMULSION FOR INFUSION | SIN16734P | INJECTION, EMULSION | 0.250g/1000ml | 3/7/2023 | |
OLIMEL N9E Emulsion for Infusion | SIN16890P | EMULSION | 1.50g/L | 10/20/2023 | |
OLICLINOMEL N4-550 E EMULSION FOR INFUSION | SIN12542P | EMULSION | 0.98 g/l | 5/6/2004 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
---|---|---|---|---|---|
No NMPA approvals found for this drug. |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
---|---|---|---|---|---|
OLIMEL N9E EMULSION FOR INFUSION | N/A | N/A | N/A | 10/24/2013 | |
PLASMA-LYTE 148 AND GLUCOSE 5% W/V SOLUTION FOR INFUSION | N/A | N/A | N/A | 8/23/2024 | |
NUTRIFLEX OMEGA SPECIAL EMULSION FOR INFUSION | N/A | N/A | N/A | 1/11/2012 | |
VOLULYTE 6% SOLUTION FOR INFUSION | N/A | N/A | N/A | 7/20/2009 | |
NUTRIFLEX OMEGA PLUS EMULSION FOR INFUSION | N/A | N/A | N/A | 1/11/2012 |
TGA Drug Approvals
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