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Sodium acetate

Generic Name
Sodium acetate
Brand Names
Bss, Bss Ophthalmic Solution, Citrasate, Clinimix E 2.75/5, Hemosate Ultra, Hyperlyte, Intersol, Isolyte P, Isolyte S, Isolyte S pH 7.4, Isoplate, Normosol-R, Olimel, Periolimel, Physiolyte, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Procalamine 3
Drug Type
Small Molecule
Chemical Formula
C2H3NaO2
CAS Number
127-09-3
Unique Ingredient Identifier
NVG71ZZ7P0

Overview

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.

Indication

Injection, USP 40 mEq is indicated as a source of sodium, for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Sodium acetate and other bicarbonate precursors are alkalinising agents, and can be used to correct metabolic acidosis, or for alkalinisation of the urine.

Associated Conditions

  • Hyponatremia
  • Hypovolaemia
  • Mild, moderate Metabolic Acidosis

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Woodward Pharma Services LLC
69784-232
INTRAVENOUS
328 mg in 1 mL
11/1/2023
Baxter Healthcare Company
0338-1147
INTRAVENOUS
340 mg in 100 mL
9/21/2020
Baxter Healthcare Corporation
0338-1147
INTRAVENOUS
340 mg in 100 mL
9/21/2020
Baxter Healthcare Company
0338-1142
INTRAVENOUS
217 mg in 100 mL
9/21/2020
Baxter Healthcare Corporation
0338-1142
INTRAVENOUS
217 mg in 100 mL
9/21/2020
B. Braun Medical Inc.
0264-7730
INTRAVENOUS
0.32 g in 100 mL
10/17/2022
Fresenius Kabi USA, LLC
65219-389
INTRAVENOUS
368 mg in 100 mL
6/18/2021
Baxter Healthcare Company
0338-7032
INTRAVENOUS
340 mg in 100 mL
4/13/2021
Baxter Healthcare Corporation
0338-7032
INTRAVENOUS
340 mg in 100 mL
4/13/2021
Baxter Healthcare Company
0338-1145
INTRAVENOUS
297 mg in 100 mL
9/21/2020

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

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