MedPath

BI-1358894

Generic Name
BI-1358894

A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood

Phase 1
Terminated
Conditions
Healthy
Interventions
First Posted Date
2023-07-07
Last Posted Date
2025-02-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
29
Registration Number
NCT05934942
Locations
🇩🇪

CRS Clinical Research Services Berlin GmbH, Berlin, Germany

A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder

Phase 2
Completed
Conditions
Post-Traumatic Stress Disorder
Interventions
Drug: Placebo
First Posted Date
2021-11-02
Last Posted Date
2024-11-07
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
318
Registration Number
NCT05103657
Locations
🇺🇸

Behavioral Research Specialists, LLC, Glendale, California, United States

🇺🇸

ASCLEPES Research Centers, P.C. dba Alliance Research, Long Beach, California, United States

🇺🇸

CalNeuro Research Group Inc., Los Angeles, California, United States

and more 58 locations

A Study in Healthy Men and Women to Test Whether BI 1358894 Influences the Amount of Bupropion in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Elontril
First Posted Date
2021-05-24
Last Posted Date
2025-02-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
18
Registration Number
NCT04899674
Locations
🇩🇪

CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany

A Study in Healthy Men to Test How BI 1358894 is Taken up and Handled by the Body

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: [14C]-radiolabelled BI 1358894
First Posted Date
2020-09-28
Last Posted Date
2025-02-27
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
15
Registration Number
NCT04567316
Locations
🇳🇱

ICON, Groningen, Netherlands

A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder

Phase 2
Completed
Conditions
Borderline Personality Disorder
Interventions
Drug: Placebo
First Posted Date
2020-09-28
Last Posted Date
2024-01-30
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
390
Registration Number
NCT04566601
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

🇦🇷

Fundación para el Estudio y Tratamiento de las Enfermedades Mentales (FETEM), Caba, Argentina

🇦🇷

Instituto Médico DAMIC S.R.L., Cordoba, Argentina

and more 64 locations

A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Phase 2
Completed
Conditions
Depressive Disorder, Major
Interventions
First Posted Date
2020-08-20
Last Posted Date
2025-03-06
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
389
Registration Number
NCT04521478
Locations
🇺🇸

CT Clinical Research, Cromwell, Connecticut, United States

🇺🇸

Institute of Living, Hartford, Connecticut, United States

🇺🇸

Gulf Coast Clinical Research Center, Fort Myers, Florida, United States

and more 117 locations

A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: BI 1358894 (C-14) intravenous solution
First Posted Date
2020-06-11
Last Posted Date
2025-03-30
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
12
Registration Number
NCT04426851
Locations
🇳🇱

ICON, Groningen, Netherlands

A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression

Phase 2
Terminated
Conditions
Depressive Disorder, Major
Interventions
Drug: Placebo
First Posted Date
2020-06-09
Last Posted Date
2023-06-13
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
45
Registration Number
NCT04423757
Locations
🇺🇸

Science 37, Inc., Culver City, California, United States

A Study in Healthy Men to Test the Influence of BI 1358894 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood

Phase 1
Completed
Conditions
Healthy
Interventions
Device: Dabigatran etexilate
First Posted Date
2019-09-23
Last Posted Date
2025-02-27
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
26
Registration Number
NCT04099732
Locations
🇩🇪

Humanpharmakologisches Zentrum Biberach, Biberach, Germany

A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Placebo
First Posted Date
2019-04-05
Last Posted Date
2025-03-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
20
Registration Number
NCT03904576
Locations
🇳🇱

ICON, Groningen, Netherlands

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