Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients
- Conditions
- Interventions
- First Posted Date
- 2010-01-07
- Last Posted Date
- 2015-06-25
- Lead Sponsor
- Aalborg University Hospital
- Target Recruit Count
- 157
- Registration Number
- NCT01043952
- Locations
- 🇩🇰
Aalborg Hospital, 4th. dept of Anaesthesiology, Division for Ear Nose and Troath anaesthesia, Aalborg, Nord Jylland, Denmark
Isoflurane Preconditioning for Liver Resections
- First Posted Date
- 2009-12-14
- Last Posted Date
- 2017-03-20
- Lead Sponsor
- Rutgers, The State University of New Jersey
- Target Recruit Count
- 8
- Registration Number
- NCT01031550
- Locations
- 🇺🇸
UMDNJ-University Hospital, Newark, New Jersey, United States
Controlled Propofol Administration
- First Posted Date
- 2009-11-25
- Last Posted Date
- 2009-11-25
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 40
- Registration Number
- NCT01019746
- Locations
- 🇨🇦
MUHC - Montreal General Hospital, Montreal, Quebec, Canada
Intraoperative Bleeding During Endoscopic Sinus Surgery
- First Posted Date
- 2009-11-17
- Last Posted Date
- 2014-02-14
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 33
- Registration Number
- NCT01014728
- Locations
- 🇺🇸
The University of Chicago, Chicago, Illinois, United States
Safety of Dexmedetomidine in Severe Traumatic Brain Injury
- Conditions
- Interventions
- First Posted Date
- 2009-11-04
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- University of Maryland, Baltimore
- Registration Number
- NCT01007773
- Locations
- 🇺🇸
University of Maryland Medical Center, Baltimore, Maryland, United States
Dexmedetomidine Versus Propofol in Vitreoretinal Surgery
- Conditions
- Interventions
- First Posted Date
- 2009-10-26
- Last Posted Date
- 2017-08-21
- Lead Sponsor
- Rutgers, The State University of New Jersey
- Target Recruit Count
- 78
- Registration Number
- NCT01001429
- Locations
- 🇺🇸
UMDNJ-University Hospital, Newark, New Jersey, United States
🇺🇸University Hospital, Newark, New Jersey, United States
Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
- First Posted Date
- 2009-10-23
- Last Posted Date
- 2017-05-19
- Lead Sponsor
- University of Athens
- Target Recruit Count
- 67
- Registration Number
- NCT01000337
- Locations
- 🇬🇷
Aretaieio Hospital, University of Athens, Athens, Attiki, Greece
Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED)
- First Posted Date
- 2009-10-19
- Last Posted Date
- 2012-04-02
- Lead Sponsor
- Hennepin Healthcare Research Institute
- Target Recruit Count
- 100
- Registration Number
- NCT00997321
- Locations
- 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Stress During Deep Sedation With Propofol With and Without Alfentanil
- First Posted Date
- 2009-10-19
- Last Posted Date
- 2014-09-25
- Lead Sponsor
- Hennepin Healthcare Research Institute
- Target Recruit Count
- 20
- Registration Number
- NCT00997113
- Locations
- 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
- First Posted Date
- 2009-10-19
- Last Posted Date
- 2017-01-27
- Lead Sponsor
- Hennepin Healthcare Research Institute
- Target Recruit Count
- 126
- Registration Number
- NCT00997126
- Locations
- 🇺🇸
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.