Pentostatin
- Generic Name
- Pentostatin
- Brand Names
- Nipent
- Drug Type
- Small Molecule
- Chemical Formula
- C11H16N4O4
- CAS Number
- 53910-25-1
- Unique Ingredient Identifier
- 395575MZO7
Overview
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Background
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Indication
For the treatment of hairy cell leukaemia refractory to alpha interferon.
Associated Conditions
- Acute Graft-Versus-Host Disease (GVHD)
- B-Lymphocytic, prolymphocytic leukemia (Kiel Classification) refractory
- Chronic Lymphocytic Leukemia
- Hairy Cell Leukemia (HCL)
- Mycosis Fungoides (MF)
- Sezary Syndrome
- Steroid refractory Chronic graft versus host disease
Clinical Trials
FDA Approved Products
Nipent
Manufacturer:Hospira, Inc.
Route:INTRAVENOUS
Strength:2 mg in 1 mL
Approved: 2023/12/20
NDC:0409-0801
Singapore Approved Products
No Singapore products found for this drug
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