Pentostatin
- Generic Name
- Pentostatin
- Brand Names
- Nipent
- Drug Type
- Small Molecule
- Chemical Formula
- C11H16N4O4
- CAS Number
- 53910-25-1
- Unique Ingredient Identifier
- 395575MZO7
- Background
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
- Indication
For the treatment of hairy cell leukaemia refractory to alpha interferon.
- Associated Conditions
- Acute Graft-Versus-Host Disease (GVHD), B-Lymphocytic, prolymphocytic leukemia (Kiel Classification) refractory, Chronic Lymphocytic Leukemia, Hairy Cell Leukemia (HCL), Mycosis Fungoides (MF), Sezary Syndrome, Steroid refractory Chronic graft versus host disease
- Associated Therapies
- -
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