Masitinib

Generic Name
Masitinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C28H30N6OS
CAS Number
790299-79-5
Unique Ingredient Identifier
M59NC4E26P
Background

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

Associated Conditions
-
Associated Therapies
-

Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19

First Posted Date
2020-11-10
Last Posted Date
2023-02-06
Lead Sponsor
AB Science
Target Recruit Count
200
Registration Number
NCT04622865
Locations
🇫🇷

Centre Hospitalier du Pays d'Aix, Aix-en-Provence, France

🇫🇷

CHU Clermont-Ferrand: Site Gabriel-Montpied, Clermont-Ferrand, France

🇫🇷

Le Tripode, Groupe hospitalier Pellegrin CHU de Bordeaux, Bordeaux, France

and more 3 locations

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment

First Posted Date
2020-04-03
Last Posted Date
2023-05-06
Lead Sponsor
AB Science
Target Recruit Count
140
Registration Number
NCT04333108
Locations
🇫🇷

Hospital Jean-Minjoz, Besançon, France

🇫🇷

Grenoble University Hospital, Grenoble, France

🇫🇷

Hospital Claude Huriez, Lille, France

and more 14 locations

Masitinib in the Treatment of Patients With Severe Uncontrolled Asthma and Elevated Eosinophil Levels

Phase 3
Completed
Conditions
Interventions
First Posted Date
2018-12-10
Last Posted Date
2020-12-08
Lead Sponsor
AB Science
Target Recruit Count
347
Registration Number
NCT03771040
Locations
🇦🇷

Centro Respiratorio Quilmes, Buenos Aires, Argentina

🇲🇾

Sarawak General Hospital, Kuching, Malaysia

🇵🇪

Clínica Universidad de los Andes, Miraflores, Peru

and more 2 locations

Masitinib Plus Gemcitabine in Pancreatic Cancer

First Posted Date
2018-12-06
Last Posted Date
2020-12-08
Lead Sponsor
AB Science
Target Recruit Count
377
Registration Number
NCT03766295
Locations
🇫🇷

Centre Hospitalier de Longjumeau, Longjumeau, France

🇬🇷

General University Hospital of Patras, Patras, Greece

🇧🇪

Hospital AZ Sint-Jan, Brugge, Belgium

and more 6 locations

Masitinib Plus Docetaxel in Metastatic Castration-resistant Prostate Cancer

First Posted Date
2018-12-03
Last Posted Date
2023-09-29
Lead Sponsor
AB Science
Target Recruit Count
714
Registration Number
NCT03761225
Locations
🇮🇳

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

🇲🇾

Universiti Malaya Medical Centre, Kuala Lumpur, Malaysia

🇨🇦

Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada

and more 6 locations

Masitinib in Combination With FOLFIRI in Third or Fourth Line of Treatment of Patients With Metastatic Colorectal Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-06-14
Last Posted Date
2020-12-08
Lead Sponsor
AB Science
Target Recruit Count
219
Registration Number
NCT03556956
Locations
🇨🇿

University Hospital Olomouc, Olomouc, Czechia

🇫🇷

Chu - Hopitaux de Rouen, Rouen, France

🇪🇸

Hospital Madrid Norte San Chinarro, Madrid, Spain

and more 2 locations

Masitinib in Combination With Gemcitabine in Advanced/Metastatic Epithelial Ovarian Cancer Patients

First Posted Date
2015-07-03
Last Posted Date
2020-12-08
Lead Sponsor
AB Science
Target Recruit Count
248
Registration Number
NCT02490488
Locations
🇩🇿

Centre hospitalo-universitaire de Beni Messous, Algiers, Algeria

🇷🇺

City Oncology Clinic, St.-Petersburg, Russian Federation

🇫🇷

Institut Sainte Catherine, Avignon, France

and more 3 locations

Masitinib in Patients With Localized, Primary GIST After Complete Surgery and With High Risk of Recurrence

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2013-12-12
Last Posted Date
2018-12-14
Lead Sponsor
AB Science
Target Recruit Count
7
Registration Number
NCT02009423

Masitinib in Patients With Mild to Moderate Alzheimer's Disease

First Posted Date
2013-06-07
Last Posted Date
2023-09-29
Lead Sponsor
AB Science
Target Recruit Count
721
Registration Number
NCT01872598
Locations
🇵🇱

Centrum Zdrowia Stołeczna 7, Białystok, Poland

🇪🇸

Hospital Universitario Ramón y Cajal, Madrid, Spain

🇬🇷

General Hospital of Thessaloniki, Thessaloniki, Greece

and more 3 locations

Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib

First Posted Date
2012-09-27
Last Posted Date
2020-12-08
Lead Sponsor
AB Science
Target Recruit Count
258
Registration Number
NCT01694277
Locations
🇫🇷

Institut Bergonié, Bordeaux, France

🇫🇷

Hôpital l'Archet 2- Service de Cancérologie Digestive, Nice, France

🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

and more 2 locations
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