Nonoxynol-9
- Generic Name
- Nonoxynol-9
- Brand Names
- Conceptrol, Gynol II, Today Sponge, Vcf Contraceptive
- Drug Type
- Small Molecule
- Chemical Formula
- C33H60O10
- CAS Number
- 26027-38-3
- Unique Ingredient Identifier
- 48Q180SH9T
- Background
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
- Indication
Nonoxynol 9 is a surfactant spermicide used for contraception in spermicidal creams, jellies, foams, gel, and lubricants. It is also used in conjuction with other methods of contraception, including condoms, cervical caps and diaphragms.
- Associated Conditions
- -
- Associated Therapies
- Contraceptive sponge therapy
A Study of the Effects of Advantage 24 on the Rectum
- Conditions
- HIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 70
- Registration Number
- NCT00000929
- Locations
- 🇺🇸
Univ of Washington, Seattle, Washington, United States
A Study of Nonoxynol-9 (N-9) and HIV Infection
- Conditions
- HIV Infections
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 4400
- Registration Number
- NCT00000926
- Locations
- 🇺🇸
Julia Welch, Research Triangle Park, North Carolina, United States
Drug Development Updates
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