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Cocaine

Generic Name
Cocaine
Brand Names
Goprelto, Numbrino
Drug Type
Small Molecule
Chemical Formula
C17H21NO4
CAS Number
50-36-2
Unique Ingredient Identifier
I5Y540LHVR

Overview

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Background

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Indication

For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

Associated Conditions

No associated conditions information available.

FDA Approved Products

COCAINE HYDROCHLORIDE
Manufacturer:LXO US INC.
Route:NASAL
Strength:40 mg in 1 mL
Approved: 2024/01/25
NDC:70839-362
cocaine hydrochloride
Manufacturer:Genus Lifesciences Inc.
Route:NASAL
Strength:40 mg in 1 mL
Approved: 2024/03/04
NDC:64950-362
cocaine hydrochloride nasal
Manufacturer:OMNIVIUM PHARMACEUTICALS LLC.
Route:TOPICAL
Strength:40 mg in 1 mL
Approved: 2023/09/25
NDC:81665-301
cocaine hydrochloride nasal
Manufacturer:Lannett Company, Inc.
Route:TOPICAL
Strength:40 mg in 1 mL
Approved: 2023/09/19
NDC:0527-1971
GOPRELTO
Manufacturer:Genus Lifesciences Inc.
Route:NASAL
Strength:40 mg in 1 mL
Approved: 2023/07/31
NDC:64950-359

Singapore Approved Products

No Singapore products found for this drug

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