Cocaine
- Generic Name
- Cocaine
- Brand Names
- Goprelto, Numbrino
- Drug Type
- Small Molecule
- Chemical Formula
- C17H21NO4
- CAS Number
- 50-36-2
- Unique Ingredient Identifier
- I5Y540LHVR
- Background
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechani...
- Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
- Associated Conditions
- -
- Associated Therapies
- -
Intranasal Cocaine and Temperature Regulation During Exercise
- First Posted Date
- 2023-04-12
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 12
- Registration Number
- NCT05809453
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Cocaine and Zolmitriptan
- Conditions
- Interventions
- First Posted Date
- 2021-08-24
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- William Stoops
- Target Recruit Count
- 20
- Registration Number
- NCT05019430
- Locations
- 🇺🇸
University of Kentucky, Lexington, Kentucky, United States
Behavioral Effects of Drugs (Inpatient): 38
- Conditions
- Interventions
- First Posted Date
- 2019-05-17
- Last Posted Date
- 2024-05-23
- Lead Sponsor
- William Stoops
- Target Recruit Count
- 5
- Registration Number
- NCT03954938
- Locations
- 🇺🇸
University of Kentucky Laboratory of Human Behavioral Pharmacology, Lexington, Kentucky, United States
Suvorexant and Cocaine
- Conditions
- Interventions
- First Posted Date
- 2019-05-06
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- William Stoops
- Target Recruit Count
- 8
- Registration Number
- NCT03937986
- Locations
- 🇺🇸
University of Kentucky, Lexington, Kentucky, United States
Behavioral Effects of Drugs: Inpatient (35)
- Conditions
- Interventions
- First Posted Date
- 2018-05-08
- Last Posted Date
- 2019-06-25
- Lead Sponsor
- Craig Rush
- Target Recruit Count
- 9
- Registration Number
- NCT03519022
- Locations
- 🇺🇸
University of Kentucky Medical Center, Lexington, Kentucky, United States
Complementary Combination Therapy for Cocaine Dependence
- Conditions
- Interventions
- First Posted Date
- 2015-09-02
- Last Posted Date
- 2022-04-26
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 45
- Registration Number
- NCT02538744
- Locations
- 🇺🇸
Michael Debakey VA Medical Center, Houston, Texas, United States
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2019-07-02
- Lead Sponsor
- William Stoops
- Target Recruit Count
- 30
- Registration Number
- NCT02522325
- Locations
- 🇺🇸
University of Kentucky Department of Behavioral Science, Lexington, Kentucky, United States
Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer
- Conditions
- Interventions
- First Posted Date
- 2015-03-09
- Last Posted Date
- 2019-04-11
- Lead Sponsor
- Joshua A. Lile, Ph.D.
- Target Recruit Count
- 18
- Registration Number
- NCT02383043
- Locations
- 🇺🇸
Laboratory of Human Behavioral Pharmacology, Lexington, Kentucky, United States
Topiramate-Phentermine Combinations for Cocaine Dependence
- Conditions
- Interventions
- First Posted Date
- 2014-09-15
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- University of Kentucky
- Target Recruit Count
- 38
- Registration Number
- NCT02239913
- Locations
- 🇺🇸
University of Kentucky Medical Center, Lexington, Kentucky, United States
Phendimetrazine and Cocaine
- First Posted Date
- 2014-09-08
- Last Posted Date
- 2017-09-27
- Lead Sponsor
- William Stoops
- Target Recruit Count
- 11
- Registration Number
- NCT02233647
- Locations
- 🇺🇸
University of Kentucky Laboratory of Human Behavioral Pharmacology, Lexington, Kentucky, United States
Drug Development Updates
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