Zolmitriptan

Generic Name
Zolmitriptan
Brand Names
Zomig
Drug Type
Small Molecule
Chemical Formula
C16H21N3O2
CAS Number
139264-17-8
Unique Ingredient Identifier
2FS66TH3YW
Background

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT) receptor agonists used to treat acute migraine. Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan,...

Indication

Zolmitriptan is indicated for the acute treatment of migraine with or without auras in patients aged 18 and over.

Associated Conditions
Cluster Headache, Migraine
Associated Therapies
-

Cocaine and Zolmitriptan

First Posted Date
2021-08-24
Last Posted Date
2024-12-12
Lead Sponsor
William Stoops
Target Recruit Count
20
Registration Number
NCT05019430
Locations
🇺🇸

University of Kentucky, Lexington, Kentucky, United States

Comparison of Oral Paracetamol and Zolmitriptan Efficacy in the Treatment of Acute Migraine in Emergency Department

Phase 4
Completed
Conditions
Interventions
First Posted Date
2017-05-09
Last Posted Date
2017-05-09
Lead Sponsor
Pamukkale University
Target Recruit Count
200
Registration Number
NCT03145467
Locations
🇹🇷

Pamukkale University, Denizli, Turkey

Safety and Pharmacokinetics (PK) Study of Single Ascending Doses of CVT-427 (Zolmitriptan Inhalation Powder) In Healthy Adults

First Posted Date
2015-11-20
Last Posted Date
2016-06-06
Lead Sponsor
Acorda Therapeutics
Target Recruit Count
21
Registration Number
NCT02609945
Locations
🇺🇸

Site 002, Dallas, Texas, United States

🇺🇸

Site 001, Daytona Beach, Florida, United States

Zomig - Treatment of Acute Migraine Headache in Adolescents

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-09-29
Last Posted Date
2016-05-18
Lead Sponsor
AstraZeneca
Target Recruit Count
1653
Registration Number
NCT01211145
Locations
🇸🇰

Research Site, Zvolen, Slovakia

ZAP, US. Zomig for Appropriate for Primary Care

Phase 4
Completed
Conditions
First Posted Date
2008-03-17
Last Posted Date
2009-04-06
Lead Sponsor
AstraZeneca
Target Recruit Count
120
Registration Number
NCT00637286

Efficacy and Tolerability of Zolmitriptan Nasal Spray

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-02-18
Last Posted Date
2009-04-06
Lead Sponsor
AstraZeneca
Target Recruit Count
2114
Registration Number
NCT00617747

Efficacy of Zolmitriptan (Zomig) in the Treatment of Migraines in Adolescents

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-02-18
Last Posted Date
2024-10-02
Lead Sponsor
Impax Laboratories, LLC
Target Recruit Count
247
Registration Number
NCT00617695
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