Quinapril
- Generic Name
- Quinapril
- Brand Names
- Accupril, Accuretic
- Drug Type
- Small Molecule
- Chemical Formula
- C25H30N2O5
- CAS Number
- 85441-61-8
- Unique Ingredient Identifier
- RJ84Y44811
- Background
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat. It is used to treat hypertension and heart failure. ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
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- Indication
Quinapril is indicated for the treatment of hypertension and as an adjunct therapy in the treatment of heart failure. Quinapril in combination with hydrochlorothiazide is indicated for the treatment of hypertension.
- Associated Conditions
- Congestive Heart Failure (CHF), Diabetic Nephropathy, Hypertension, Left Ventricular Dysfunction
- Associated Therapies
- -
Diabetic Autonomic Neuropathy and Left Ventricular Function
- Conditions
- Interventions
- First Posted Date
- 2023-02-06
- Last Posted Date
- 2023-02-06
- Lead Sponsor
- AHEPA University Hospital
- Target Recruit Count
- 59
- Registration Number
- NCT05713396
- Locations
- 🇬🇷
Diabetes Center, 1st Propeudetic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, "AHEPA'' Hospital, Thessaloníki, Greece
Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus
- Conditions
- First Posted Date
- 2017-01-26
- Last Posted Date
- 2017-01-26
- Lead Sponsor
- Aristotle University Of Thessaloniki
- Registration Number
- NCT03031834
A Non Interventional Study To Asses The Safety, Effectiveness And Tolerability Of Quinapril (Acupil®) In An Indian Population
- First Posted Date
- 2009-06-30
- Last Posted Date
- 2011-05-04
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 329
- Registration Number
- NCT00930722
- Locations
- 🇮🇳
Pfizer Investigational Site, Kolkata, West Bengal, India
Management With Accupril Post Bypass Graft
- Conditions
- First Posted Date
- 2005-12-23
- Last Posted Date
- 2006-02-08
- Lead Sponsor
- Montreal Heart Institute
- Registration Number
- NCT00269243
QWISE - Study of Quinapril in Women With Chest Pain, Coronary Flow Reserve Limitations and Evidence of Myocardial Ischemia
- First Posted Date
- 2005-09-08
- Last Posted Date
- 2012-04-13
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 78
- Registration Number
- NCT00150826
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
- Conditions
- First Posted Date
- 2005-09-07
- Last Posted Date
- 2007-04-30
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 70
- Registration Number
- NCT00147524
- Locations
- 🇭🇺
Pfizer Investigational Site, Szombathely, Hungary
Drug Development Updates
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