Overview
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Background
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Indication
Investigated for the treatment of cancer.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2009/08/04 | Phase 2 | Completed | |||
2009/08/04 | Phase 2 | Completed | |||
2007/10/12 | Phase 1 | Completed | |||
2006/06/05 | Phase 1 | Completed | |||
2006/02/15 | Phase 1 | Completed | |||
2006/02/15 | Phase 2 | Completed | |||
2003/05/07 | Phase 1 | Completed |
FDA Approved Products
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No FDA products found
No FDA products found for this drug
EMA Approved Products
Product Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
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No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval Number |
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No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval Number | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|---|---|---|---|---|---|---|---|---|
国药准字H10960135 | 软膏剂 | N/A | 10g:3mg;30g:9mg | Chemical Drug | Approved | 2020/07/27 | Domestic | ||
国药准字H20054000 | 软膏剂 | N/A | 10g:3mg | Chemical Drug | Approved | 2019/09/30 | Domestic |
PPB Approved Products
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No PPB products found
No PPB products found for this drug
TGA Approved Products
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No TGA products found
No TGA products found for this drug