Prilocaine

Generic Name: Prilocaine

Brand Names: Agoneaze, Anodyne Lpt, Citanest, Citanest Forte, Dermacinrx Prikaan, Emla, Fortacin, Lido Bdk, Lido-prilo Caine Pack, Lidopril, Oraqix, Prilolid, Prizotral, Relador

Drug Type: Small Molecule

Chemical Formula: C_₁₃H_₂₀N_₂O

CAS Number: 721-50-6

Unique Ingredient Identifier: 046O35D44R

Background: A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

Indication: 适用于硬膜外麻醉、阻滞麻醉和浸润麻醉等。

Associated Conditions: -

Associated Therapies: Local Anaesthesia therapy

Clinical Trials

Comparison of Infraclavicular Brachial Plexus Block and Local Anesthesia in Arteriovenous Fistula Surgeries and Their Effects on Tissue Oxygen Saturation

Not Applicable

Completed

Conditions: Renal Disease, Chronic

Interventions: Device: NIRS
Drug: Prilocaine
Other: Pinprick Test
Other: Modified Bromage Scale
Drug: Bupivacaine

First Posted Date: 2024-05-16

Last Posted Date: 2025-01-10

Lead Sponsor: Ankara City Hospital Bilkent

Target Recruit Count: 60

Registration Number: NCT06416111

Locations: 🇹🇷
Ankara Bilkent City Hospital, Ankara, Çankaya, Turkey

Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section

Not Applicable

Not yet recruiting

Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Interventions: Drug: Bupivacaine
Drug: Prilocaine

First Posted Date: 2024-03-04

Last Posted Date: 2024-03-05

Lead Sponsor: South Valley University

Target Recruit Count: 60

Registration Number: NCT06290583

Topical Anaesthesia in Cutaneous Head and Neck Surgery

Not Applicable

Completed

Conditions: Pain, Acute
Head and Neck Cancer
Cutaneous Tumor

Interventions: Drug: Aqueous cream BP
Drug: EMLA
Drug: Ethyl chloride

First Posted Date: 2024-02-23

Last Posted Date: 2024-02-23

Lead Sponsor: University Hospital Waterford

Target Recruit Count: 124

Registration Number: NCT06274905

Locations: 🇮🇪
University Hospital Waterford, Waterford, Ireland

Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients

Phase 3

Recruiting

Conditions: Hemodynamic Instability

Interventions: Drug: Prilocaine
Drug: Bupivacaine

First Posted Date: 2023-12-11

Last Posted Date: 2024-07-23

Lead Sponsor: Cairo University

Target Recruit Count: 112

Registration Number: NCT06165679

Locations: 🇪🇬
Kasr Alaini hospital, Cairo, Egypt

Effect of Prilocaine on Motor Block During Caesarean Section

Phase 4

Completed

Conditions: Spinal for Caesarean Section

Interventions: Drug: prilocaine
Drug: bupivacaine

First Posted Date: 2023-11-18

Last Posted Date: 2024-02-28

Lead Sponsor: Cairo University

Target Recruit Count: 40

Registration Number: NCT06133881

Locations: 🇪🇬
Faculty of Medicine Cairo University, Cairo, Egypt

Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy Procedure

Phase 4

Active, not recruiting

Conditions: Anesthesia
Anesthesia; Reaction

Interventions: Drug: Prilocaine

First Posted Date: 2022-11-08

Last Posted Date: 2022-11-08

Lead Sponsor: Indonesia University

Target Recruit Count: 66

Registration Number: NCT05610007

Locations: 🇮🇩
Cipto Mangunkusumo Cental National Hospital, Jakarta, DKI Jakarta, Indonesia

Prilocaine for Spinal Anesthesia in Ambulatory Setting

Completed

Conditions: Prilocaine
Anesthesia, Spinal
Ambulatory Surgical Procedures

First Posted Date: 2019-11-13

Last Posted Date: 2019-11-13

Lead Sponsor: Ospedale di Circolo - Fondazione Macchi

Target Recruit Count: 3291

Registration Number: NCT04161586

Locations: 🇮🇹
Department of Day Surgery Ospedale di Circolo Varese, Varese, VA, Italy

Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures

Phase 4

Completed

Conditions: Leukemia-Lymphoma

Interventions: Drug: EMLA
Drug: Lidocaine

First Posted Date: 2019-07-01

Last Posted Date: 2023-03-09

Lead Sponsor: CAMC Health System

Target Recruit Count: 10

Registration Number: NCT04003012

Locations: 🇺🇸
CAMC - Women and Children's Hospital, Charleston, West Virginia, United States

Pain Perception During Vulvar Biopsy

Phase 4

Terminated

Conditions: Any Condition Requiring Vulvar Biopsy

Interventions: Drug: Lidocaine
Drug: EMLA

First Posted Date: 2018-08-31

Last Posted Date: 2020-01-18

Lead Sponsor: Duke University

Target Recruit Count: 37

Registration Number: NCT03654417

Locations: 🇺🇸
Duke Univeristy, Durham, North Carolina, United States

Pharmacokinetic Study of Nanoencapsulated Gel of Lidocaine, Prilocaine and Combination of Lidocaine and Prilocaine

Phase 1

Completed

Conditions: Topical Anesthesia

Interventions: Drug: Lidocaine + Prilocaine
Drug: Lidocaine
Drug: Prilocaine

First Posted Date: 2018-02-22

Last Posted Date: 2018-02-22

Lead Sponsor: Galeno Desenvolvimento de Pesquisas Clínicas

Target Recruit Count: 48

Registration Number: NCT03441841

Locations: 🇧🇷
Galeno Desenvolvimento de Pesquisas Clinicas Ltda. - ME, Campinas, SP, Brazil

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