Romiplostim
- Generic Name
- Romiplostim
- Brand Names
- Nplate
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 267639-76-9
- Unique Ingredient Identifier
- GN5XU2DXKV
- Background
Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently attache...
- Indication
Treatment of chronic immune thrombocytopenic purpura.
- Associated Conditions
- Chronic immune thrombocytopenia, Refractory immune thrombocytopenia
- Associated Therapies
- -
Romiplostim, Rituximab and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia
- Conditions
- Interventions
- First Posted Date
- 2020-10-19
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- David Gomez Almaguer
- Target Recruit Count
- 12
- Registration Number
- NCT04588194
- Locations
- 🇲🇽
Servicio de Hematología, Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico
TPO-Mimetic Use in Children for Hematopoietic Failure
- Conditions
- Interventions
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Anjali Sharathkumar
- Target Recruit Count
- 15
- Registration Number
- NCT04478227
- Locations
- 🇺🇸
University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States
Using Romiplostim to Treat Low Platelet Counts Following Chemotherapy and Autologous Hematopoietic Cell Transplantation in People With Blood Cancer
- Conditions
- Interventions
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 62
- Registration Number
- NCT04478123
- Locations
- 🇺🇸
Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown, New Jersey, United States
🇺🇸Memorial Sloan Kettering Commack (Limited Protocol Activities), Commack, New York, United States
🇺🇸Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey, United States
Efficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome
- First Posted Date
- 2020-05-01
- Last Posted Date
- 2020-05-06
- Target Recruit Count
- 30
- Registration Number
- NCT04371939
- Locations
- 🇷🇺
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
Romiplostim Treatment for Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome.
- First Posted Date
- 2020-04-16
- Last Posted Date
- 2020-12-28
- Target Recruit Count
- 67
- Registration Number
- NCT04350164
- Locations
- 🇷🇺
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation
Study of AMG531 (Romiplostim) in Patients With Aplastic Anemia
- First Posted Date
- 2019-09-19
- Last Posted Date
- 2022-05-26
- Lead Sponsor
- Kyowa Kirin Co., Ltd.
- Target Recruit Count
- 24
- Registration Number
- NCT04095936
- Locations
- 🇯🇵
NTT Medical center Tokyo, Shinagawa, Tokyo, Japan
Study of AMG531(Romiplostim) in Patients With Aplastic Anemia
- First Posted Date
- 2019-05-21
- Last Posted Date
- 2022-05-26
- Lead Sponsor
- Kyowa Kirin Co., Ltd.
- Target Recruit Count
- 17
- Registration Number
- NCT03957694
- Locations
- 🇯🇵
Matsuyama Red Cross Hospital, Ehime, Japan
Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2019-05-03
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- Amgen
- Target Recruit Count
- 162
- Registration Number
- NCT03937154
- Locations
- 🇺🇸
Saint Bernards Medical Center, Jonesboro, Arkansas, United States
🇺🇸Los Angeles Cancer Network, Anaheim, California, United States
🇺🇸Hattiesburg Clinic Hematology/Oncology, Hattiesburg, Mississippi, United States
Patients With Relapsed Ovarian Cancer (2nd and 3rd Line) Treated With Chemotherapy According to AGO Guidelines
- Conditions
- Interventions
- First Posted Date
- 2018-08-09
- Last Posted Date
- 2021-02-08
- Target Recruit Count
- 21
- Registration Number
- NCT03622931
- Locations
- 🇩🇪
Praxisklinik für Krebsheilkunde für Frauen Drs. Kittel /Klare / Wetzel, Berlin, Germany
🇩🇪Charité Campus Virchow-Klinikum Universitätsmedizin Berlin, Berlin, Germany
🇩🇪Ev. Waldkrankenhaus Spandau, Berlin, Germany
Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
- Conditions
- Interventions
- First Posted Date
- 2017-12-05
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- Amgen
- Target Recruit Count
- 162
- Registration Number
- NCT03362177
- Locations
- 🇵🇹
Centro Hospitalar Universitario de Sao Joao, EPE - Hospital Sao Joao, Porto, Portugal
🇷🇺Autonomic SHI Republican clinical oncology dispensary of MoH of the Republic of Tatarstan, Kazan, Russian Federation
🇷🇺Clinical hospital 2, Group of companies medsi, Moscow, Russian Federation
Drug Development Updates
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