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Azenosertib

Generic Name
Azenosertib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C29H34N8O2
CAS Number
2376146-48-2
Unique Ingredient Identifier
9J13XU96Z1
Associated Conditions
-
Associated Therapies
-

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Phase 1
Recruiting
Conditions
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Metastatic Gastroesophageal Junction Adenocarcinoma
Unresectable Gastric Carcinoma
Unresectable Gastroesophageal Junction Adenocarcinoma
Unresectable Malignant Solid Neoplasm
Clinical Stage III Gastric Cancer AJCC v8
Locally Advanced Gastroesophageal Junction Adenocarcinoma
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Locally Advanced Gastric Carcinoma
Interventions
Drug: Azenosertib
Procedure: Biospecimen Collection
Procedure: Biopsy
Procedure: Computed Tomography
Procedure: Echocardiography
Procedure: Magnetic Resonance Imaging
Procedure: Multigated Acquisition Scan
Biological: Trastuzumab Deruxtecan
First Posted Date
2024-04-15
Last Posted Date
2024-12-03
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
48
Registration Number
NCT06364410
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

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