Eszopiclone

Generic Name
Eszopiclone
Brand Names
Lunesta
Drug Type
Small Molecule
Chemical Formula
C17H17ClN6O3
CAS Number
138729-47-2
Unique Ingredient Identifier
UZX80K71OE
Background

Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones. Cyclopyrrolone drugs demonstrate high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia.
...

Indication

Eszopiclone is indicated for the treatment of insomnia.

Associated Conditions
Insomnia
Associated Therapies
-

Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome

First Posted Date
2009-01-14
Last Posted Date
2016-12-20
Lead Sponsor
University of Arizona
Target Recruit Count
5
Registration Number
NCT00822679
Locations
🇺🇸

Southern Arizona VA Health Care System, Tucson, Arizona, United States

Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-12-23
Last Posted Date
2012-10-03
Lead Sponsor
Lehigh Center for Clinical Research
Target Recruit Count
60
Registration Number
NCT00813735
Locations
🇺🇸

Lehigh Center for Clinical Research, Allentown, Pennsylvania, United States

Treatment of Insomnia in Migraineurs

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-12-22
Last Posted Date
2023-06-15
Lead Sponsor
MedVadis Research Corporation
Target Recruit Count
113
Registration Number
NCT00812214

Treatment of Insomnia and Glucose Metabolism

First Posted Date
2008-07-29
Last Posted Date
2015-10-16
Lead Sponsor
University of Chicago
Target Recruit Count
20
Registration Number
NCT00724282
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

Safety and Efficacy of Eszopiclone With Mild to Moderate Obstructive Sleep Apnea Syndrome (OSAS)

First Posted Date
2008-05-28
Last Posted Date
2012-02-22
Lead Sponsor
Sumitomo Pharma America, Inc.
Target Recruit Count
20
Registration Number
NCT00685269

Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia

First Posted Date
2008-03-28
Last Posted Date
2015-07-16
Lead Sponsor
Yale University
Target Recruit Count
39
Registration Number
NCT00645944
Locations
🇺🇸

Connecticut Mental Health Center, New Haven, Connecticut, United States

Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD Subjects

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-02-15
Last Posted Date
2016-04-08
Lead Sponsor
Sumitomo Pharma America, Inc.
Target Recruit Count
456
Registration Number
NCT00616655
Locations
🇺🇸

Southwestern Research, Inc., Pasadena, California, United States

🇺🇸

Excell Research, Oceanside, California, United States

🇺🇸

California Clinical Trials Medical Group, Paramount, California, United States

and more 41 locations

Continuous Positive Airway Pressure (CPAP) Promotion And Prognosis - the Army Sleep Apnea Program (ASAP)

First Posted Date
2008-02-11
Last Posted Date
2009-02-26
Lead Sponsor
Walter Reed Army Medical Center
Target Recruit Count
154
Registration Number
NCT00612157
Locations
🇺🇸

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Eszopiclone for Improving Sleep in Multiple Sclerosis (MS)

First Posted Date
2008-01-15
Last Posted Date
2009-01-05
Lead Sponsor
University of Vermont
Target Recruit Count
30
Registration Number
NCT00594087
Locations
🇺🇸

University of Vermont, Burlington, Vermont, United States

Sleep Loss and Mechanisms of Impaired Glucose Metabolism

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2007-11-09
Last Posted Date
2013-12-10
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
20
Registration Number
NCT00555750
Locations
🇺🇸

Brigham and Women's Hospital, Division of Sleep Medicine, Boston, Massachusetts, United States

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