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Fosaprepitant

Generic Name
Fosaprepitant
Brand Names
Emend, Focinvez, Ivemend
Drug Type
Small Molecule
Chemical Formula
C23H22F7N4O6P
CAS Number
172673-20-0
Unique Ingredient Identifier
6L8OF9XRDC

Overview

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.

Background

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.

Indication

Fosaprepitant is indicated in adult and pediatric patients ≥6 months of age, in combination with other antiemetic agents, for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy, including high-dose cisplatin. It is also indicated for the treatment of delayed nausea and vomiting with initial and repeat courses of moderately emetogenic cancer chemotherapy.

Associated Conditions

  • Acute Chemotherapy-Induced Nausea and Vomiting (CINV) caused by highly emetogenic chemotherapy
  • Delayed Chemotherapy-Induced Nausea and Vomiting (CINV) caused by highly emetogenic chemotherapy
  • Delayed Chemotherapy-Induced Nausea and Vomiting (CINV) caused by moderately emetogenic chemotherapy

FDA Approved Products

Fosaprepitant
Manufacturer:MSN LABORATORIES PRIVATE LIMITED
Route:INTRAVENOUS
Strength:150 mg in 5 mL
Approved: 2019/12/26
NDC:69539-034
Fosaprepitant
Manufacturer:NorthStar RxLLC
Route:INTRAVENOUS
Strength:150 mg in 5 mL
Approved: 2023/07/25
NDC:16714-248
FOSAPREPITANT DIMEGLUMINE
Manufacturer:Eugia US LLC
Route:INTRAVENOUS
Strength:150 mg in 5 mL
Approved: 2023/10/12
NDC:55150-299
Fosaprepitant
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAVENOUS
Strength:150 mg in 5 mL
Approved: 2020/06/29
NDC:63323-972
fosaprepitant
Manufacturer:Zydus Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:150 mg in 5 mL
Approved: 2022/12/20
NDC:70710-1615

Singapore Approved Products

No Singapore products found for this drug

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