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Calcipotriol

Generic Name
Calcipotriol
Brand Names
Calcitrene, Dovobet, Dovonex, Enstilar, Sorilux, Taclonex, Wynzora
Drug Type
Small Molecule
Chemical Formula
C27H40O3
CAS Number
112965-21-6
Unique Ingredient Identifier
143NQ3779B
Background

Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.

Indication

For the treatment of moderate plaque psoriasis in adults.

Associated Conditions
Plaque psoriasis of the scalp, Psoriasis Vulgaris (Plaque Psoriasis)

PSOREAL - Managing PSOriasis in the REAL World

Completed
Conditions
Psoriasis Vulgaris
Interventions
First Posted Date
2016-10-17
Last Posted Date
2021-06-14
Lead Sponsor
LEO Pharma
Target Recruit Count
1214
Registration Number
NCT02935582
Locations
🇸🇪

Psoriasis association in Stockholm region, Stockholm, Sweden

🇨🇦

Dr. Chih-Ho Hong Medical Inc., Surrey, British Columbia, Canada

🇬🇧

Layton Medical Centre, Blackpool, Lancashire, United Kingdom

Efficacy and Tolerability of Enstilar® in Daily Practice

Completed
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2016-08-29
Last Posted Date
2019-12-13
Lead Sponsor
LEO Pharma
Target Recruit Count
410
Registration Number
NCT02881346
Locations
🇩🇪

Clinic for Dermatology, Venereology and Allergy, University Clinic Schleswig-Holstein, Kiel, Germany

Adherence in Topical Treatment of Psoriasis

Phase 4
Completed
Conditions
Adherence
Interventions
First Posted Date
2016-08-08
Last Posted Date
2019-06-03
Lead Sponsor
Odense University Hospital
Target Recruit Count
134
Registration Number
NCT02858713
Locations
🇩🇰

Department of Dermatology and Allergy Centre, Odense C, Denmark

A Trial That Compound Clobetasol Propionate Ointment Treats Patients With Mild to Moderate Psoriasis Vulgaris.

First Posted Date
2016-04-12
Last Posted Date
2016-04-14
Lead Sponsor
First Hospital of China Medical University
Target Recruit Count
240
Registration Number
NCT02733874

Comparative Effectiveness Trial in the Treatment of Pediatric Plaque Morphea

Phase 1
Withdrawn
Conditions
Scleroderma
Interventions
First Posted Date
2016-02-11
Last Posted Date
2018-07-18
Lead Sponsor
Medical College of Wisconsin
Registration Number
NCT02680717

LEO 80185 Gel (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Psoriasis

Phase 3
Completed
Conditions
Psoriasis Vulgaris
Interventions
Drug: LEO 80185 gel
First Posted Date
2016-01-29
Last Posted Date
2025-03-10
Lead Sponsor
LEO Pharma
Target Recruit Count
213
Registration Number
NCT02668692
Locations
🇯🇵

Medical Corporation Bikyukai Kokubu Dermatology, Kitami-shi, Hokkaido, Japan

Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis

Phase 3
Conditions
Psoriasis
Interventions
Drug: Placebo
Drug: Topical Coal tar
First Posted Date
2016-01-01
Last Posted Date
2016-01-01
Lead Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Target Recruit Count
40
Registration Number
NCT02644954

Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis

Phase 3
Completed
Conditions
Nail Psoriasis
Interventions
Drug: Vehicle of P-3073
First Posted Date
2015-11-17
Last Posted Date
2018-03-08
Lead Sponsor
Polichem S.A.
Target Recruit Count
378
Registration Number
NCT02606760

A Psoriasis Plaque Test Trial With LP0113 Spray in Patients With Psoriasis Vulgaris (LP0113-1123)

Phase 2
Completed
Conditions
Skin and Connective Tissue Diseases
Interventions
Drug: Aerosol spray vehicle
Drug: LP0113 aerosol spray
Drug: LEO 90100 aerosol foam
Drug: Daivobet® gel
First Posted Date
2015-04-14
Last Posted Date
2025-02-24
Lead Sponsor
LEO Pharma
Target Recruit Count
50
Registration Number
NCT02416258
Locations
🇫🇷

Centre de Pharmacologie Clinique Appliquée à la Dermatologie (CPCAD), Nice, France

Molecular Effects of Topical Calcipotriene on Morphea

Early Phase 1
Terminated
Conditions
Morphea
Localized Scleroderma
Interventions
First Posted Date
2015-04-08
Last Posted Date
2018-09-13
Lead Sponsor
Northwestern University
Target Recruit Count
2
Registration Number
NCT02411643
Locations
🇺🇸

Northwestern University Feinberg School of Medicine, Department of Dermatology, Chicago, Illinois, United States

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