MedPath

Zinc gluconate

Generic Name
Zinc gluconate
Drug Type
Small Molecule
Chemical Formula
C12H22O14Zn
CAS Number
4468-02-4
Unique Ingredient Identifier
U6WSN5SQ1Z

Overview

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , . Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary. Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks . More information about Zinc (in its natural form) is available at Zinc.

Background

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , . Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary. Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks . More information about Zinc (in its natural form) is available at Zinc.

Indication

Zinc gluconate is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea .

Associated Conditions

  • Zinc Deficiency

Clinical Trials

Early Phase 1
Recruiting
Posted: 2019/05/21
Sponsor:
Second Affiliated Ho...
Not Applicable
Completed
Posted: 2016/11/01
Sponsor:
Chang Gung Memorial ...
Phase 1
Posted: 2013/11/14
Sponsor:
Main Line Health

FDA Approved Products

Floriva
Manufacturer:BonGeo Pharmaceuticals, Inc.
Route:ORAL
Strength:5 mg in 1 1
Approved: 2024/02/02
NDC:52796-174
Zyvana
Manufacturer:Sterling-Knight Pharmaceuticals, LLC
Route:ORAL
Strength:23 mg in 1 1
Approved: 2021/02/22
NDC:69336-405
Floriva
Manufacturer:BonGeo Pharmaceuticals, Inc.
Route:ORAL
Strength:5 mg in 1 1
Approved: 2024/02/01
NDC:52796-177
Maxi/Guard Oral Cleansing Gel
Manufacturer:H & C Animal Health LLC
Route:ORAL
Strength:0.022 g in 1 mL
Approved: 2025/04/08
NDC:86137-4159
OraZn
Manufacturer:Addison Biological Laboratory, Inc.
Route:ORAL
Strength:.0165 g in 1 mL
Approved: 2025/04/08
NDC:86045-9200

Singapore Approved Products

ZINC AGUETTANT CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML
Manufacturer:Laboratoire AGUETTANT
Form:INFUSION, SOLUTION CONCENTRATE
Strength:1mg/mL
Online:Yes
Approved: 2023/04/25
Approval:SIN16768P

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath