MedPath

Matrix-M

Generic Name
Matrix-M
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
YZ7P8Y8ECX
Background

Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.

Associated Conditions
-
Associated Therapies
-

Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative Persons

Phase 1
Active, not recruiting
Conditions
Epstein-Barr Virus Infection
Infectious Mononucleosis
Herpesvirus
Interventions
Other: Placebo Comparator
Drug: Matrix-M1 Adjuvant
Drug: EBV gp350-Ferritin Vaccine
First Posted Date
2023-01-13
Last Posted Date
2024-12-09
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1000
Registration Number
NCT05683834
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

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