MedPath

Flurbiprofen

Generic Name
Flurbiprofen
Drug Type
Small Molecule
Chemical Formula
C15H13FO2
CAS Number
5104-49-4
Unique Ingredient Identifier
5GRO578KLP

Overview

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.

Background

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.

Indication

Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.

Associated Conditions

  • Ankylosing Spondylitis (AS)
  • Back Pain, Acute
  • Chronic Back Pain
  • Menstrual Distress (Dysmenorrhea)
  • Muscle Spasms
  • Non-Articular Rheumatic Muscle Spasms
  • Osteoarthritis (OA)
  • Pain
  • Pain, Inflammatory
  • Post Traumatic Pain
  • Postoperative pain
  • Rheumatoid Arthritis
  • Spinal pain

FDA Approved Products

Flurbiprofen
Manufacturer:PD-Rx Pharmaceuticals, Inc.
Route:ORAL
Strength:100 mg in 1 1
Approved: 2023/03/31
NDC:43063-992
Flurbiprofen
Manufacturer:NuCare Pharmaceuticals,Inc.
Route:ORAL
Strength:100 mg in 1 1
Approved: 2021/07/20
NDC:68071-2480
Flurbiprofen
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:100 mg in 1 1
Approved: 2021/11/30
NDC:63629-8808
Flurbiprofen
Manufacturer:Preferred Pharmaceuticals Inc.
Route:ORAL
Strength:100 mg in 1 1
Approved: 2023/06/13
NDC:68788-7341
Flurbiprofen
Manufacturer:Teva Pharmaceuticals USA, Inc.
Route:ORAL
Strength:100 mg in 1 1
Approved: 2021/11/30
NDC:0093-0711

Singapore Approved Products

STREPSILS MAX PRO DIRECT SPRAY 8.75MG PER DOSE
Manufacturer:Reckitt Benckiser Healthcare Manufacturing (Thailand) Ltd
Form:SPRAY
Strength:8.7480mg/dose
Online:Yes
Approved: 2017/11/29
Approval:SIN15370P
ACUSTOP CATAPLASMA PLASTER 40 mg/sheet
Manufacturer:GC BIOPHARMA CORP.
Form:PATCH
Strength:40 mg/sheet
Online:Yes
Approved: 2002/09/30
Approval:SIN12090P
Strepsils MaxPro Honey and Lemon lozenges 8.75mg
Manufacturer:Reckitt Benckiser Healthcare Manufacturing (Thailand) Limited
Form:LOZENGE
Strength:8.75mg
Online:Yes
Approved: 2013/06/11
Approval:SIN14364P

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