Hyaluronic acid

Generic Name
Hyaluronic acid
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C28H44N2O23
CAS Number
9004-61-9
Unique Ingredient Identifier
S270N0TRQY
Background

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...

Indication

The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...

Associated Conditions
Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
Associated Therapies
Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication

Combined Effect of Insulin and Sodium Hyaluronate Injection Guided by Ultrasound in Carpal Tunnel Syndrome

First Posted Date
2019-10-29
Last Posted Date
2019-10-29
Lead Sponsor
Assiut University
Target Recruit Count
90
Registration Number
NCT04142411
Locations
🇪🇬

Medicine, Assiut, Egypt

Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis

First Posted Date
2019-10-17
Last Posted Date
2019-10-17
Lead Sponsor
CAR-T (Shanghai) Biotechnology Co., Ltd.
Target Recruit Count
60
Registration Number
NCT04130100
Locations
🇨🇳

Changhai hospital, Shanghai, China

Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury

First Posted Date
2019-05-20
Last Posted Date
2020-09-16
Lead Sponsor
Qilu Hospital of Shandong University
Target Recruit Count
30
Registration Number
NCT03955497
Locations
🇨🇳

Qilu hospital of Shandong University, Jinan, Shandong, China

Effect of Different Injection Regimens of Autologous Conditioned Plasma for Knee Osteoarthritis

First Posted Date
2019-03-26
Last Posted Date
2023-01-31
Lead Sponsor
Andrews Research & Education Foundation
Target Recruit Count
60
Registration Number
NCT03889925
Locations
🇺🇸

Andrews Institute for Orthopaedics & Sports Medicine, Gulf Breeze, Florida, United States

The Comparison of Knee Osteoarthritis Treatment With Bone Marrow Aspirate Concentrate , Leukocyte Rich Platelet Rich Plasma and Hyaluronic Acid

First Posted Date
2019-01-31
Last Posted Date
2019-02-07
Lead Sponsor
Clinical Center of Vojvodina
Target Recruit Count
180
Registration Number
NCT03825133
Locations
🇷🇸

Clinical Center of Vojvodina, Novi Sad, Vojvodina, Serbia

Implantation of Allogenic Mesenchymal Stem Cell From Umbilical Cord Blood for Osteoarthritis Management

First Posted Date
2019-01-11
Last Posted Date
2019-01-23
Lead Sponsor
Indonesia University
Target Recruit Count
9
Registration Number
NCT03800810
Locations
🇮🇩

Universitas Indonesia, Jakarta Pusat, Jakarta, Indonesia

the Effect of Topical Application of Hyaluronic Acid on Immediate Dental Implant

First Posted Date
2018-10-01
Last Posted Date
2021-06-08
Lead Sponsor
Ibrahim Samy Kalboush
Target Recruit Count
24
Registration Number
NCT03691467
Locations
🇪🇬

Cairo University, Cairo, Egypt

What Factors Are Associated With Prognosis of Rotator Cuff Disorder After Subacromial Hyaluronic Acid Injection

Not Applicable
Conditions
Interventions
First Posted Date
2018-09-19
Last Posted Date
2018-10-10
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
200
Registration Number
NCT03677895
Locations
🇨🇳

Taipei Veterans General Hospital, Taipei, Taiwan

The Effect of Platelet Rich Plasma Injection Combined With Exercise Rehabilitation in Patients With Rotator Cuff Tear

First Posted Date
2018-06-07
Last Posted Date
2018-06-07
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
30
Registration Number
NCT03548662
Locations
🇨🇳

Taipei veteran general hospital, Taipei, Taiwan

Treatment of Osteoarthrosis of the Knee With Platelet Rich Plasma, Comparative Study With Hyaluronic Acid

First Posted Date
2018-03-26
Last Posted Date
2022-06-16
Lead Sponsor
Karla Andrea Arias Varela
Target Recruit Count
28
Registration Number
NCT03477630
Locations
🇨🇷

Hospital Clínica Bíblica, San José, Costa Rica

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