Alprostadil
- Generic Name
- Alprostadil
- Brand Names
- Caverject, Edex, Muse, Prostin Vr
- Drug Type
- Small Molecule
- Chemical Formula
- C20H34O5
- CAS Number
- 745-65-3
- Unique Ingredient Identifier
- F5TD010360
- Background
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment is either...
- Indication
Alprostadil is indicated for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. It is also indicated for the treatment of erectile dysfunction due to neurogenic...
- Associated Conditions
- Erectile Dysfunction, Patent Ductus Arteriosus (PDA), Raynaud's Phenomenon
- Associated Therapies
- -
The Use of Prostaglandin E1 in Head and Neck Microsurgery
- Conditions
- Interventions
- First Posted Date
- 2008-08-13
- Last Posted Date
- 2009-10-27
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 242
- Registration Number
- NCT00733434
- Locations
- 🇨🇳
National taiwan University Hospital, Taipei, Taiwan
ALP-1 Continuous Intravenous Infusion to Maintain Clinical Stability in Advanced Heart Failure
- First Posted Date
- 2008-02-07
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- Biopeutics Co., Ltd
- Target Recruit Count
- 1500
- Registration Number
- NCT00610051
- Locations
- 🇦🇹
Medical university Vienna, Vienna, Austria
Alprostadil in Peripheral Arterial Occlusive Disease (PAOD) Stage IV
- Conditions
- Interventions
- First Posted Date
- 2008-01-17
- Last Posted Date
- 2018-04-04
- Lead Sponsor
- UCB BIOSCIENCES GmbH
- Target Recruit Count
- 840
- Registration Number
- NCT00596752
- Locations
- 🇨🇿
414, Usti Nad Labem, Czechia
🇨🇿404, Plzen, Czechia
🇲🇽505, Merida, Mexico
ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted Prostatectomy for Prostate Cancer
- First Posted Date
- 2007-10-16
- Last Posted Date
- 2019-01-02
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 110
- Registration Number
- NCT00544076
- Locations
- 🇺🇸
City of Hope, Duarte, California, United States
Drug Development Updates
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