Chlorhexidine

Generic Name
Chlorhexidine
Brand Names
Betasept, Hibiclens, Instillagel, Nupro Chlorhexidine, Oris, Oro-Clense, Paroex, Perichlor, Peridex, Periochip, Periogard, Prevora, X-pur
Drug Type
Small Molecule
Chemical Formula
C22H30Cl2N10
CAS Number
55-56-1
Unique Ingredient Identifier
R4KO0DY52L
Background

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings a...

Indication

Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release "chip" which is inserted into periodo...

Associated Conditions
Aphthous ulcer, Catarrh of the throat, Chemotherapy Induced Oral Mucositis, Chronic Wounds, Decubitus Ulcer, Dental Cavity, Dysphagia, Eczema infected, Foeter Ex Ore, Gingival Bleeding, Gingival Diseases, Gingivitis, Glossitis, Hoarseness, Infection, Infectious Periodontal Diseases, Injury Throat, Mild to Moderate Inflammatory Reaction of the Oral Cavity, Mild to Moderate Inflammatory Reaction of the Pharynx, Mouth injury, Mucositis, Neurodermatitis, Ocular Inflammation, Ocular Irritation, Oral Aphthous Ulcer, Pain, Periodontitis, Pharyngitis, Plaque, Dental, Postoperative Wound Infection, Purulent Gingivitis, Radiation Mucositis, Red eye, Ringworm, Skin Infections, Sore Throat, Stomatitis, Surgical Wounds, Tissue Damage, Tonsillitis, Ulcers, Leg, Wound Infections, Bacterial skin infections, Dry, cracked skin, Gum pain, Moderate Gingivitis, Oral infections, Oral lesions, Recurrent Oral fungal infection, Severe Gingivitis, Superficial Wounds, Throat disinfection, Tongue inflammation
Associated Therapies
Anesthesia of Mucous Membrane, Antimicrobial Therapy, Contact Lens Care, Disinfection, Disinfection of External Genitalia, Disinfection of the Urethra, Disinfection of the Vaginal Mucosa, Irrigation therapy, Lubrication of the Urethra, Oral Care, Oral Hygiene, Oropharyngeal antisepsis, Promotion of wound healing, Skin disinfection, Surgical Scrubbing, Topical Antisepsis, Urethral Anesthesia, Wound Cleansing, Oral antisepsis, Oral disinfection

The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids

Phase 2
Completed
Conditions
Interventions
First Posted Date
2019-07-24
Last Posted Date
2020-10-08
Lead Sponsor
Julie Dawson
Target Recruit Count
38
Registration Number
NCT04031131
Locations
🇬🇧

Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk, United Kingdom

BPO vs Hibiclens Soap for Surgical Preparation

First Posted Date
2019-07-16
Last Posted Date
2022-03-15
Lead Sponsor
University of Washington
Target Recruit Count
50
Registration Number
NCT04021524
Locations
🇺🇸

University of Washington, Seattle, Washington, United States

Chlorohexidine Versus Povidone Iodine as Apreoperative Ophthalmic Disinfectant

First Posted Date
2019-05-21
Last Posted Date
2019-05-21
Lead Sponsor
Assiut University
Target Recruit Count
100
Registration Number
NCT03957291

Non-surgical Treatment of Peri-implant Mucositis

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2019-04-16
Last Posted Date
2022-05-17
Lead Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Target Recruit Count
74
Registration Number
NCT03915665
Locations
🇮🇹

IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth

First Posted Date
2019-02-26
Last Posted Date
2020-04-10
Lead Sponsor
Nourhan M.Aly
Target Recruit Count
60
Registration Number
NCT03855527
Locations
🇪🇬

Faculty of Dentistry, Alexandria University, Alexandria, Egypt

Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery

First Posted Date
2018-11-15
Last Posted Date
2018-11-15
Lead Sponsor
University of Pecs
Target Recruit Count
50
Registration Number
NCT03741894
Locations
🇭🇺

Department of Oral and Maxillofacial Surgery, University of Pécs, Pécs, Hungary

2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2018-10-09
Last Posted Date
2023-03-08
Lead Sponsor
University of Southern California
Target Recruit Count
40
Registration Number
NCT03700788
Locations
🇺🇸

Herman Ostrow USC School of Dentistry, Los Angeles, California, United States

Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients

First Posted Date
2018-09-26
Last Posted Date
2020-02-28
Lead Sponsor
Cairo University
Target Recruit Count
63
Registration Number
NCT03684993
Locations
🇪🇬

Faculty of Dentistry Cairo University, Cairo, Egypt

Chitosan,Chitosan Nanoparticles,and Chlorhexidine Gluconate, as Intra Canal Medicaments in Primary Teeth

First Posted Date
2018-07-17
Last Posted Date
2018-07-17
Lead Sponsor
Ain Shams University
Target Recruit Count
45
Registration Number
NCT03588351
Locations
🇪🇬

Ain shames university faculty of dentistry, Cairo, Egypt

© Copyright 2024. All Rights Reserved by MedPath