Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells (City of Hope Medical Center)
- Generic Name
- Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells (City of Hope Medical Center)
Memory Enriched T Cells Following Stem Cell Transplant in Treating Patients With Recurrent B-Cell Non-Hodgkin Lymphoma
Phase 1
Active, not recruiting
- Conditions
- Recurrent Mantle Cell LymphomaRefractory Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell LymphomaRefractory Mantle Cell LymphomaTransformed Recurrent Non-Hodgkin Lymphoma
- Interventions
- Biological: Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytesOther: Laboratory Biomarker Analysis
- First Posted Date
- 2014-01-31
- Last Posted Date
- 2025-05-01
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 51
- Registration Number
- NCT02051257
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma
Phase 1
Active, not recruiting
- Conditions
- Recurrent Adult Grade III Lymphomatoid GranulomatosisSmall Intestine LymphomaCutaneous B-cell Non-Hodgkin LymphomaIntraocular LymphomaRecurrent Grade 2 Follicular LymphomaRecurrent Marginal Zone LymphomaRecurrent Adult Diffuse Mixed Cell LymphomaRecurrent Adult Immunoblastic Large Cell LymphomaRecurrent Adult Burkitt LymphomaRecurrent Adult Diffuse Large Cell Lymphoma
- Interventions
- Procedure: autologous hematopoietic stem cell transplantationOther: laboratory biomarker analysis
- First Posted Date
- 2013-03-21
- Last Posted Date
- 2024-12-31
- Lead Sponsor
- City of Hope Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT01815749
- Locations
- 🇺🇸
City of Hope Medical Center, Duarte, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.
© Copyright 2025. All Rights Reserved by MedPath