Esmolol
- Generic Name
- Esmolol
- Brand Names
- Brevibloc
- Drug Type
- Small Molecule
- Chemical Formula
- C16H25NO4
- CAS Number
- 81147-92-4
- Unique Ingredient Identifier
- MDY902UXSR
- Background
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decrea...
- Indication
For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention.
- Associated Conditions
- Hypertension, Tachycardia, Abnormal ventricular rate, Heart rate abnormal
- Associated Therapies
- -
Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery
- Conditions
- Interventions
- First Posted Date
- 2024-10-01
- Last Posted Date
- 2024-10-01
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT06620991
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
REMAP ECMO - Beta Receptor Modulation Trial
- First Posted Date
- 2024-07-26
- Last Posted Date
- 2024-07-26
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT06522594
- Locations
- 🇳🇱
Erasmus Medical Center, Rotterdam, Zuid Holland, Netherlands
Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes
- Conditions
- Interventions
- First Posted Date
- 2024-04-30
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- Lin Chen
- Target Recruit Count
- 150
- Registration Number
- NCT06390748
- Locations
- 🇨🇳
Sichuan Provincial People's Hospital, Chengdu, Sichuan, China
Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy
- Conditions
- Interventions
- First Posted Date
- 2024-02-20
- Last Posted Date
- 2024-02-20
- Lead Sponsor
- Khon Kaen University
- Target Recruit Count
- 90
- Registration Number
- NCT06268275
- Locations
- 🇹🇭
Khon Kaen University, Khon Kaen, Naimuang, Muang, Thailand
Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome
- First Posted Date
- 2023-08-28
- Last Posted Date
- 2024-03-13
- Lead Sponsor
- Zhiming Jiang
- Target Recruit Count
- 178
- Registration Number
- NCT06013319
- Locations
- 🇨🇳
Department of Intensive Care Medicine, Jinan, Shandong, China
Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study
- First Posted Date
- 2023-05-09
- Last Posted Date
- 2023-05-09
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 60
- Registration Number
- NCT05850832
- Locations
- 🇪🇬
Alexandria University Faculty of Medicin, Alexandria, Egypt
Effect of Esmolol on Perioperative Stress Reaction
- Conditions
- Interventions
- First Posted Date
- 2023-01-23
- Last Posted Date
- 2023-01-23
- Lead Sponsor
- Xiumei Song
- Target Recruit Count
- 46
- Registration Number
- NCT05694585
Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients
- First Posted Date
- 2022-12-02
- Last Posted Date
- 2023-03-29
- Lead Sponsor
- Yongtao Sun
- Target Recruit Count
- 2000
- Registration Number
- NCT05635877
- Locations
- 🇨🇳
Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University, Jinan, Shandong, China
Effects of Heart Control at Different Stages in Patients of Septic Shock With Tachycardia
- First Posted Date
- 2022-05-25
- Last Posted Date
- 2022-05-25
- Lead Sponsor
- Chinese Medical Association
- Target Recruit Count
- 96
- Registration Number
- NCT05389176
Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy
- First Posted Date
- 2021-10-11
- Last Posted Date
- 2021-10-11
- Target Recruit Count
- 80
- Registration Number
- NCT05073094
- Locations
- 🇷🇺
E. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation
Drug Development Updates
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