膦甲酸钠 (Foscavir)

概览

Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections.

作用机制

Foscarnet exerts its antiviral activity by a selective inhibition at the pyrophosphate binding site on virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases.

适应症

For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients.

• Chickenpox
• Cytomegalovirus Retinitis
• Herpes Simplex Infections