MedPath

Trabedersen

Generic Name
Trabedersen
Drug Type
Biotech
CAS Number
925681-61-4
Unique Ingredient Identifier
98OYR854NY
Indication

Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

Phase 1
Not yet recruiting
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2024-08-30
Last Posted Date
2025-04-10
Lead Sponsor
University of Nebraska
Target Recruit Count
45
Registration Number
NCT06579196
Locations
🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

OT-101 in Combination With Atezolizumab for the Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer

Phase 2
Withdrawn
Conditions
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Metastatic Lung Non-Small Cell Carcinoma
Interventions
Biological: Atezolizumab
Procedure: Biopsy
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Other: Electronic Health Record Review
Procedure: Magnetic Resonance Imaging
First Posted Date
2023-07-07
Last Posted Date
2023-08-25
Lead Sponsor
University of Washington
Registration Number
NCT05935774
Locations
🇺🇸

Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma

Phase 3
Terminated
Conditions
Anaplastic Astrocytoma
Glioblastoma
Interventions
Device: Drug delivery system for administration of AP 12009
Procedure: Placement of Drug Delivery System
First Posted Date
2008-09-29
Last Posted Date
2014-11-14
Lead Sponsor
Isarna Therapeutics GmbH
Target Recruit Count
27
Registration Number
NCT00761280
Locations
🇦🇷

FLENI, Ciudad Autónoma de Buenos Aires, Argentina

🇺🇸

NJ Neuroscience Institute; JFK Medical Center, Edison, New Jersey, United States

🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

and more 64 locations
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