Overview
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone. Morphine was granted FDA approval in 1941.
Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone. Morphine was granted FDA approval in 1941.
Indication
Morphine is used for the management of chronic, moderate to severe pain. Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
Associated Conditions
- Chronic Pain
- Severe Pain
Clinical Trials
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Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2018/02/12 | Phase 3 | Completed | |||
2018/02/12 | Phase 4 | Completed | University Tunis El Manar | ||
2018/02/09 | Phase 2 | Completed | Asklepieion Voulas General Hospital | ||
2018/02/09 | N/A | Recruiting | Kanecia Obie Zimmerman | ||
2018/02/07 | Not Applicable | Completed | Bursa Yüksek İhtisas Education and Research Hospital | ||
2018/02/07 | Phase 1 | Completed | |||
2018/01/29 | Phase 2 | UNKNOWN | |||
2018/01/19 | Phase 4 | Completed | |||
2018/01/17 | Phase 2 | UNKNOWN | John Granton | ||
2018/01/11 | Phase 3 | Completed |
FDA Drug Approvals
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| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
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HSA Drug Approvals
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NMPA Drug Approvals
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PPB Drug Approvals
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TGA Drug Approvals
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