MedPath

Insulin icodec/Semaglutide

Generic Name
Insulin icodec/Semaglutide

A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)

Phase 3
Active, not recruiting
Conditions
Type 2 Diabetes
Interventions
First Posted Date
2024-02-21
Last Posted Date
2025-04-17
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
474
Registration Number
NCT06269107
Locations
🇺🇸

Methodist Phys. Clinic, Omaha, Nebraska, United States

🇺🇸

Albuquerque Clin Trials, Inc., Albuquerque, New Mexico, United States

🇺🇸

Albany Medical College - Endo, Albany, New York, United States

and more 86 locations

A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or Together

Phase 1
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2022-06-28
Last Posted Date
2025-03-21
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
20
Registration Number
NCT05435677
Locations
🇨🇳

Peking University Third Hospital, Northern branch-Phase I, Beijing, Beijing, China

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec

Phase 3
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2022-04-29
Last Posted Date
2025-04-03
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
1291
Registration Number
NCT05352815
Locations
🇺🇸

Endeavor Health, Skokie, Illinois, United States

🇵🇹

Unidade Local De Saude Da Regiao De Aveiro E.P.E., Aveiro, Portugal

🇳🇴

St. Olavs Hospital HF, Trondheim, Norway

and more 205 locations

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)

Phase 3
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2022-02-28
Last Posted Date
2025-01-17
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
683
Registration Number
NCT05259033
Locations
🇺🇸

Endeavor Health, Skokie, Illinois, United States

🇨🇳

Zhu Xianyi Memorial Hospital of Tianjin Medical University-Endocrinology, Tianjin, Tianjin, China

🇺🇸

Pri Med Grp dba/Gil Ctr Fam, Gilbert, Arizona, United States

and more 130 locations

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3)

Phase 3
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
First Posted Date
2021-08-19
Last Posted Date
2024-11-14
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
679
Registration Number
NCT05013229
Locations
🇺🇸

Endeavor Health, Skokie, Illinois, United States

🇺🇸

Andres Garcia-Zuniga, MD, P.A, Laredo, Texas, United States

🇫🇷

Centre de Recherche Clinique Portes Du Sud, Venissieux, France

and more 126 locations
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