Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
-

Effects Of Single Doses Of GW784568X On Allergic Rhinitis Symptoms In Male Subjects Whilst In An Environmental Chamber

First Posted Date
2006-11-29
Last Posted Date
2017-09-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
45
Registration Number
NCT00404586
Locations
🇩🇪

GSK Investigational Site, Hannover, Niedersachsen, Germany

A Dose-Finding Study Evaluating Safety and Efficacy in Patients With Chronic Obstructive Pulmonary Disease

First Posted Date
2006-11-23
Last Posted Date
2009-06-30
Lead Sponsor
Dey
Target Recruit Count
457
Registration Number
NCT00403286
Locations
🇺🇸

Research Site, Milwaukee, Wisconsin, United States

Investigate Two Trial Models; Vienna Challenge Chamber (in and Out of Season) and Park Study (in Season) Using a Drug for Seasonal Allergic Rhinitis

First Posted Date
2006-11-17
Last Posted Date
2018-01-10
Lead Sponsor
Research Consult GmbH
Target Recruit Count
41
Registration Number
NCT00400998
Locations
🇦🇹

GSK Investigational Site, Vienna, Austria

Study on the Effects of an AMP Challenge on Asthmatic Patients Following Treatment With Fluticasone Propionate

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-11-17
Last Posted Date
2016-09-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
49
Registration Number
NCT00400855
Locations
🇳🇿

GSK Investigational Site, Wellington, New Zealand

Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)

First Posted Date
2006-11-02
Last Posted Date
2018-07-02
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
182
Registration Number
NCT00395304
Locations
🇺🇸

Kaiser Permanente Medical Center, San Diego, California, United States

🇺🇸

National Jewish Medical and Research Center, Denver, Colorado, United States

🇺🇸

University of Wisconsin - Madison, Madison, Wisconsin, United States

and more 2 locations

Exercise Study in Patient With Chronic Obstructive Pulmonary Disease (0000-036)

First Posted Date
2006-10-12
Last Posted Date
2016-01-21
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
12
Registration Number
NCT00387036

Seretide Versus Flixotide In Asthmatic Children Not Controlled By Inhaled Corticosteroids

First Posted Date
2006-07-19
Last Posted Date
2018-05-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
506
Registration Number
NCT00353873
Locations
🇸🇪

GSK Investigational Site, Stockholm, Sweden

Exploration Of Key Targets And Biomarkers Involved In An Allergic Response In Subjects With Allergic Rhinitis (Hay Fever)

Phase 1
Completed
Conditions
First Posted Date
2006-07-04
Last Posted Date
2008-10-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
48
Registration Number
NCT00348361
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA)

First Posted Date
2006-04-27
Last Posted Date
2018-03-23
Lead Sponsor
Milton S. Hershey Medical Center
Target Recruit Count
92
Registration Number
NCT00318708
Locations
🇺🇸

Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

🇺🇸

National Jewish Medical and Research Center, Denver, Colorado, United States

🇺🇸

University of California, San Francisco, San Francisco, California, United States

and more 7 locations

Viapaed Study In Children And Adolescents With Asthma

First Posted Date
2006-04-19
Last Posted Date
2017-10-19
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
285
Registration Number
NCT00315744
Locations
🇩🇪

GSK Investigational Site, Hamburg, Germany

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