Haloperidol

Generic Name
Haloperidol
Brand Names
Haldol
Drug Type
Small Molecule
Chemical Formula
C21H23ClFNO2
CAS Number
52-86-8
Unique Ingredient Identifier
J6292F8L3D
Background

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularl...

Indication

Haloperidol is indicated for a number of conditions including for the treatment of schizophrenia, for the manifestations of psychotic disorders, for the control of tics and vocal utterances of Tourette’s Disorder in children and adults, for treatment of severe behavior problems in children of combative, explosive hyperexcitability (which cannot be accounted ...

Associated Conditions
Aggression, Delirium, Gilles de la Tourette's Syndrome, Huntington's Disease (HD), Nausea and vomiting, Obsessive Compulsive Disorder (OCD), Psychosis, Schizophrenia, Severe Disruptive Behaviour Disorders, Severe Hyperactivity
Associated Therapies
-

Valproic Acid for Treatment of Hyperactive or Mixed Delirium in ICU

First Posted Date
2015-01-22
Last Posted Date
2019-06-26
Lead Sponsor
Stanford University
Target Recruit Count
3
Registration Number
NCT02343575
Locations
🇺🇸

Stanford Hospital and Clinics, Stanford, California, United States

Antipsychotic Effects of Sorghum Bicolor (JOBELYN) in the Treatment of Schizophrenia

First Posted Date
2014-09-15
Last Posted Date
2017-02-16
Lead Sponsor
Federal Neuro-Psychiatric Hospital, Yaba
Target Recruit Count
100
Registration Number
NCT02240173
Locations
🇳🇬

Federal Neuro-Psychiatric Hospital Yaba - Lagos, Lagos, Nigeria

Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

First Posted Date
2014-08-12
Last Posted Date
2017-04-13
Lead Sponsor
Indiana University
Target Recruit Count
135
Registration Number
NCT02213900
Locations
🇺🇸

University Hospital, Indianapolis, Indiana, United States

D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement

First Posted Date
2014-07-30
Last Posted Date
2016-04-25
Lead Sponsor
Centre for Addiction and Mental Health
Target Recruit Count
60
Registration Number
NCT02203786
Locations
🇨🇦

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Lurasidone Effects on Tissue Glutamate in Schizophrenia

First Posted Date
2014-07-24
Last Posted Date
2021-03-01
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
35
Registration Number
NCT02199743
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital

Phase 4
Withdrawn
Conditions
Interventions
First Posted Date
2014-04-04
Last Posted Date
2017-07-24
Lead Sponsor
Hennepin Healthcare Research Institute
Registration Number
NCT02103881

Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the Emergency Department: A Randomized Controlled Trial

First Posted Date
2014-03-28
Last Posted Date
2014-03-28
Lead Sponsor
United States Naval Medical Center, Portsmouth
Target Recruit Count
68
Registration Number
NCT02098499
Locations
🇺🇸

Naval Medical Center Portsmouth, Portsmouth, Virginia, United States

Haloperidol vs Conventional Therapy for Gastroparesis

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2014-02-07
Last Posted Date
2017-08-17
Lead Sponsor
The University of Texas Health Science Center, Houston
Target Recruit Count
36
Registration Number
NCT02057549
Locations
🇺🇸

Lyndon Baines Johnson General Hospital, Houston, Texas, United States

Drug Interactions With Risk of QT-prolongation in a General Hospital

Completed
Conditions
Interventions
First Posted Date
2014-01-23
Last Posted Date
2014-06-11
Lead Sponsor
KU Leuven
Target Recruit Count
222
Registration Number
NCT02043912
Locations
🇧🇪

Universitair Ziekenhuis Leuven, Leuven, Belgium

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