Haloperidol

Generic Name
Haloperidol
Brand Names
Haldol
Drug Type
Small Molecule
Chemical Formula
C21H23ClFNO2
CAS Number
52-86-8
Unique Ingredient Identifier
J6292F8L3D
Background

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularl...

Indication

Haloperidol is indicated for a number of conditions including for the treatment of schizophrenia, for the manifestations of psychotic disorders, for the control of tics and vocal utterances of Tourette’s Disorder in children and adults, for treatment of severe behavior problems in children of combative, explosive hyperexcitability (which cannot be accounted ...

Associated Conditions
Aggression, Delirium, Gilles de la Tourette's Syndrome, Huntington's Disease (HD), Nausea and vomiting, Obsessive Compulsive Disorder (OCD), Psychosis, Schizophrenia, Severe Disruptive Behaviour Disorders, Severe Hyperactivity
Associated Therapies
-

Comparison of Intramuscular Olanzapine and Intramuscular Haloperidol in Patients With Schizophrenia

Phase 3
Completed
Conditions
First Posted Date
2007-06-13
Last Posted Date
2007-06-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
50
Registration Number
NCT00485901
Locations
🇨🇳

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Taipei, Taiwan

A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room

First Posted Date
2007-04-06
Last Posted Date
2019-07-26
Lead Sponsor
University of Southern California
Target Recruit Count
72
Registration Number
NCT00457366
Locations
🇺🇸

Los Angeles County Hospital, Los Angeles, California, United States

Pilot Study of Haloperidol to Treat Critical Illness Delirium

Phase 2
Completed
Conditions
First Posted Date
2007-02-01
Last Posted Date
2012-11-14
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
20
Registration Number
NCT00429676
Locations
🇺🇸

Denver Health Medical Center, Denver, Colorado, United States

Modulation of Regional Brain Activation in Schizophrenic Patients by Pharmacological Therapy

First Posted Date
2007-01-09
Last Posted Date
2008-09-16
Lead Sponsor
University of Jena
Target Recruit Count
19
Registration Number
NCT00419653

Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression

First Posted Date
2006-06-21
Last Posted Date
2014-08-19
Lead Sponsor
Duke University
Target Recruit Count
72
Registration Number
NCT00340379
Locations
🇺🇸

University of Southern California, Los Angeles, California, United States

🇪🇬

Alexandria University, Alexandria, Egypt

🇮🇳

National Institute of Mental Health and Neuroscience, Bangalore, India

ORIC-I: Optimizing Recovery From Intensive Care: Mechanical Ventilation and Delirium

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2006-03-08
Last Posted Date
2017-12-20
Lead Sponsor
University of Pittsburgh
Target Recruit Count
40
Registration Number
NCT00300391

A Comparison of Risperidone With Haloperidol in Patients With Schizophrenia and Schizoaffective Disorder

First Posted Date
2005-11-15
Last Posted Date
2012-08-06
Lead Sponsor
Janssen, LP
Target Recruit Count
396
Registration Number
NCT00253110

Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery

First Posted Date
2005-11-08
Last Posted Date
2009-08-07
Lead Sponsor
Bronovo Hospital
Target Recruit Count
220
Registration Number
NCT00250237
Locations
🇳🇱

Bronovo Hospital, The Hague, Zuid Holland, Netherlands

Efficacy Study of Switching Stabilized Schizophrenic Patients From Conventional to Atypical Antipsychotic Treatment

Phase 4
Completed
Conditions
First Posted Date
2005-09-19
Last Posted Date
2012-06-12
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
360
Registration Number
NCT00191555
Locations
🇫🇷

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon-Fri 9AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) , or speak with your personal physician, Villejuif, France

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