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(R)-Gossypol

Generic Name
(R)-Gossypol
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C30H30O8
CAS Number
90141-22-3
Unique Ingredient Identifier
8DY2X8LXW4
Background

(R)-Gossypol is the R-isomer of Gossypol.

Associated Conditions
-
Associated Therapies
-

Gossypol, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1
Completed
Conditions
Adult Grade III Lymphomatoid Granulomatosis
Adult Nasal Type Extranodal NK/T-cell Lymphoma
Contiguous Stage II Adult Burkitt Lymphoma
Contiguous Stage II Adult Diffuse Large Cell Lymphoma
Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma
Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma
Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma
Contiguous Stage II Adult Lymphoblastic Lymphoma
Contiguous Stage II Grade 1 Follicular Lymphoma
Contiguous Stage II Grade 2 Follicular Lymphoma
Interventions
First Posted Date
2009-04-30
Last Posted Date
2013-01-10
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
36
Registration Number
NCT00891072
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Gossypol Acetic Acid in Treating Patients With Recurrent, Metastatic, or Primary Adrenocortical Cancer That Cannot Be Removed By Surgery

Phase 2
Completed
Conditions
Recurrent Adrenocortical Carcinoma
Stage III Adrenocortical Carcinoma
Stage IV Adrenocortical Carcinoma
Interventions
First Posted Date
2009-02-20
Last Posted Date
2014-05-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
29
Registration Number
NCT00848016
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Southern California, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic, Rochester, Minnesota, United States

R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

Phase 2
Completed
Conditions
Extensive Stage Small Cell Lung Cancer
Recurrent Small Cell Lung Cancer
Interventions
Drug: R-(-)-gossypol acetic acid
Other: pharmacological study
Other: laboratory biomarker analysis
First Posted Date
2008-10-16
Last Posted Date
2014-05-12
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
15
Registration Number
NCT00773955
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic, Rochester, Minnesota, United States

R-(-)-Gossypol Acetic Acid, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer

Phase 1
Completed
Conditions
Extensive Stage Small Cell Lung Cancer
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
First Posted Date
2007-10-16
Last Posted Date
2014-04-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
27
Registration Number
NCT00544596
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UW Health Oncology - 1 South Park, Madison, Wisconsin, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

๐Ÿ‡บ๐Ÿ‡ธ

Sanford Cancer Center-Oncology Clinic, Sioux Falls, South Dakota, United States

and more 1 locations

Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Phase 2
Completed
Conditions
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Recurrent Adult Brain Tumor
Interventions
Drug: R-(-)-gossypol acetic acid
Other: laboratory biomarker analysis
First Posted Date
2007-10-08
Last Posted Date
2017-08-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
56
Registration Number
NCT00540722
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Pennsylvania, Philadelphia, Pennsylvania, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins University, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Moffitt Cancer Center, Tampa, Florida, United States

and more 5 locations
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