Erythromycin

Generic Name
Erythromycin
Brand Names
Aktipak, Apo-Erythro-S, Benzamycin, E.E.S., Ery, Ery-tab, Erygel, Eryped, Erythro, Erythrocin, Erythrocin Stearate
Drug Type
Small Molecule
Chemical Formula
C37H67NO13
CAS Number
114-07-8
Unique Ingredient Identifier
63937KV33D
Background

Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections,...

Indication

Erythromycin is indicated in the treatment of infections caused by susceptible strains of various bacteria. The indications for erythromycin have been summarized by body system below:

Respiratory infections
...

Associated Conditions
Acne, Acne Vulgaris, Acute Otitis Media caused by Haemophilus Influenzae, Acute pelvic inflammatory disease caused by Neisseria Gonorrheae Infection, Bacterial Infections, Chancroid, Chlamydia Trachomatis, Chlamydial ophthalmia neonatorum, Community Acquired Pneumonia (CAP), Diphtheria, Erythrasma, Gastroparesis, Granuloma Inguinale, Intestinal amebiasis caused by entamoeba histolytica, Legionella Pneumophila Infections, Listeria infection, Lower Respiratory Tract Infection (LRTI), Lymphogranuloma Venereum, Nongonococcal urethritis, Ophthalmia neonatorum (gonococcal), Pertussis, Postoperative Infections, Primary Syphilis, Respiratory Tract Infections (RTI), Skin and skin structure infections, Staphylococcal Skin Infections, Syphilis, Upper Respiratory Tract Infection, Ureaplasma urethritis, Whooping Cough, Inflammatory papular lesions, Mild Acne vulgaris, Moderate Acne vulgaris, Predominant skin comedones, papules and pustules, Prophylaxis of Rheumatic fever, Pustular lesions, Skin and subcutaneous tissue bacterial infections caused by streptococcus pyogenes, Superficial ocular infections
Associated Therapies
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Clinical Trials
Related News

Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility

First Posted Date
2011-06-23
Last Posted Date
2016-03-21
Lead Sponsor
Mayo Clinic
Target Recruit Count
40
Registration Number
NCT01379183
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

An Investigation of the Effects of Erythromycin on the Pharmacokinetics of the Pregabalin Controlled Release Tablet

First Posted Date
2011-04-27
Last Posted Date
2021-01-22
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Target Recruit Count
18
Registration Number
NCT01342198
Locations
🇧🇪

Pfizer Investigational Site, Bruxelles, Belgium

Selections of Subjects With Important Changes in Their Cardiac Repolarization Parameters for the Procurement of Skin and Blood Samples

Phase 1
Completed
Conditions
Cardiology: RR / QT
Interventions
Drug: Placebo
Drug: Erythromycin
First Posted Date
2011-04-19
Last Posted Date
2011-09-15
Lead Sponsor
Ectycell SASU
Target Recruit Count
130
Registration Number
NCT01338441
Locations
🇫🇷

BIOTRIAL, Rueil Malmaison, France

TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r)

First Posted Date
2011-03-25
Last Posted Date
2012-10-11
Lead Sponsor
Tibotec Pharmaceuticals, Ireland
Target Recruit Count
49
Registration Number
NCT01323257

Comparison of Two Macrolides, Azithromycin and Erythromycin, for Symptomatic Treatment of Gastroparesis

Phase 2
Terminated
Conditions
Gastroparesis
Interventions
Drug: Erythromycin
Drug: Azithromycin
First Posted Date
2011-03-25
Last Posted Date
2014-12-05
Lead Sponsor
University of Florida
Target Recruit Count
26
Registration Number
NCT01323582
Locations
🇺🇸

University of Florida, Gainesville, Florida, United States

Methylnaltrexone vs Erythromycin for Facilitating Gastric Emptying Time in Critically Ill Patients

Phase 2
Terminated
Conditions
Gastroparesis
Interventions
Drug: Erythromycin
Drug: Methylnaltrexone
First Posted Date
2010-05-05
Last Posted Date
2011-03-31
Lead Sponsor
Shiraz University of Medical Sciences
Target Recruit Count
42
Registration Number
NCT01117376
Locations
🇮🇷

Nemazee Hospital, Shiraz, Fars, Iran, Islamic Republic of

Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy

First Posted Date
2010-04-02
Last Posted Date
2010-04-28
Lead Sponsor
UPECLIN HC FM Botucatu Unesp
Target Recruit Count
20
Registration Number
NCT01097811
Locations
🇧🇷

Faculdade de Medicina de Botucatu - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Intravenous Erythromycin Before Endoscopy in Patients With Variceal Bleeding: A Randomized, Double-Blind Trial

Not Applicable
Completed
Conditions
Variceal Bleeding
Interventions
Drug: Placebo
Drug: Erythromycin
First Posted Date
2010-02-02
Last Posted Date
2010-02-02
Lead Sponsor
King Abdulaziz Medical City
Target Recruit Count
102
Registration Number
NCT01060267
Locations
🇸🇦

King Abdul Aziz Medical City, Riyadh 11426, Saudi Arabia

Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube

Phase 4
Completed
Conditions
Pancreatitis
Interventions
Drug: Placebo
Drug: Erythromycin
First Posted Date
2009-10-21
Last Posted Date
2010-01-22
Lead Sponsor
Canisius-Wilhelmina Hospital
Registration Number
NCT00999232

The Effect of Intravenous Erythromycin on Gastric Emptying in Non-fasted Patients Before Emergency Total Anesthesia

First Posted Date
2009-01-22
Last Posted Date
2015-06-23
Lead Sponsor
University Hospital, Geneva
Target Recruit Count
132
Registration Number
NCT00827216
Locations
🇨🇭

University Hospital of Geneva, Geneva, Switzerland

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