Ibuprofen

Generic Name
Ibuprofen
Brand Names
Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
Drug Type
Small Molecule
Chemical Formula
C13H18O2
CAS Number
15687-27-1
Unique Ingredient Identifier
WK2XYI10QM
Background

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication

Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions
Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
Associated Therapies
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Comparision Between Paracetamol and Ibuprofen in Closure of Patent Ductus Arteriosus

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-12-01
Last Posted Date
2023-12-01
Lead Sponsor
Assiut University
Target Recruit Count
56
Registration Number
NCT06152796

Effect of Acetaminophen Versus Ibuprofen in Treating Recurrent Apthous Ulcers in Pediatric Celiac Disease

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-11-29
Last Posted Date
2023-12-28
Lead Sponsor
Cairo University
Target Recruit Count
12
Registration Number
NCT06149507

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

First Posted Date
2023-10-31
Last Posted Date
2023-10-31
Lead Sponsor
Heron Therapeutics
Target Recruit Count
30
Registration Number
NCT06109415
Locations
🇺🇸

First Surgical Hospital, Bellaire, Texas, United States

🇺🇸

Legent Orthopedic Hospital, Carrollton, Texas, United States

🇺🇸

JBR Clinical Research, Salt Lake City, Utah, United States

and more 2 locations

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

First Posted Date
2023-10-31
Last Posted Date
2023-10-31
Lead Sponsor
Heron Therapeutics
Target Recruit Count
30
Registration Number
NCT06109428
Locations
🇺🇸

Endeavor Clinical Trials, LLC, San Antonio, Texas, United States

🇺🇸

First Surgical Hospital, Bellaire, Texas, United States

A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants

First Posted Date
2023-10-11
Last Posted Date
2024-06-28
Lead Sponsor
H. Lundbeck A/S
Target Recruit Count
26
Registration Number
NCT06077786
Locations
🇳🇱

Centre for Human Drug Research, Leiden, Netherlands

Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients

First Posted Date
2023-09-29
Last Posted Date
2024-01-08
Lead Sponsor
Ankara City Hospital Bilkent
Target Recruit Count
84
Registration Number
NCT06061575
Locations
🇹🇷

Ankara City Hospital, Ankara, Turkey

Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery

First Posted Date
2023-07-07
Last Posted Date
2024-10-10
Lead Sponsor
University of Nove de Julho
Target Recruit Count
34
Registration Number
NCT05935306
Locations
🇺🇾

Universidade Catolica do Uruguay, Montevideo, Uruguay

NSAID Use After Robotic Partial Nephrectomy

First Posted Date
2023-05-03
Last Posted Date
2024-10-08
Lead Sponsor
University of Miami
Target Recruit Count
110
Registration Number
NCT05842044
Locations
🇺🇸

University of Miami, Miami, Florida, United States

Intravenous Ibuprofen Postoperative Analgesia After Abdominal Hysterectomy

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2023-03-01
Last Posted Date
2024-01-26
Lead Sponsor
Menoufia University
Target Recruit Count
152
Registration Number
NCT05750264
Locations
🇪🇬

Faculty of Medicine, Cairo, Shebin Elkom, Egypt

Post-operative Pain Management in Children With Supracondylar Humerus Fractures

First Posted Date
2022-12-07
Last Posted Date
2023-09-13
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
100
Registration Number
NCT05640674
Locations
🇺🇸

Texas Children's Hospital - West Campus, Houston, Texas, United States

🇺🇸

Texas Children's Hospital - Woodlands Campus, Houston, Texas, United States

🇺🇸

Texas Children's Hospital - Main Campus, Houston, Texas, United States

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