Ibuprofen

Generic Name
Ibuprofen
Brand Names
Addaprin, Advil, Advil Cold and Sinus, Advil Congestion Relief, Advil PM, Advil Sinus Congestion and Pain, Alivio, Caldolor, Cedaprin, Children's Ibuprofen, Diphen, Duexis, Ibu, Ibutab, Junior Strength Motrin, Motrin, Motrin PM, Neoprofen, Nuprin, Pedea, Proprinal, Reprexain, Sudafed PE Head Congestion Plus Pain, Vicoprofen, Wal-profen Congestion Relief and Pain, Ibuprofen Gen.Orph
Drug Type
Small Molecule
Chemical Formula
C13H18O2
CAS Number
15687-27-1
Unique Ingredient Identifier
WK2XYI10QM
Background

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and this drug was first ...

Indication

Ibuprofen is the most commonly used and prescribed NSAID. It is a very common over-the-counter medication widely used as an analgesic, anti-inflammatory and antipyretic.
...

Associated Conditions
Acute Pain, Ankylosing Spondylitis (AS), Common Cold, Cystic Fibrosis (CF), Fever, Gastric Ulcer, Gout, Headache, Insomnia, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Mild pain, Nasal Congestion, Osteoarthritis (OA), Pain, Pain, Inflammatory, Patent Ductus Arteriosus (PDA), Pericarditis, Primary Dysmenorrhoea, Rheumatoid Arthritis, Severe Pain, Sinus pressure, Mild to moderate pain, Minor aches and pains, Moderate Pain
Associated Therapies
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Ibuprofen Plus Acetaminophen for Enhanced Pain Reduction

First Posted Date
2020-11-16
Last Posted Date
2022-04-14
Lead Sponsor
New York City Health and Hospitals Corporation
Target Recruit Count
100
Registration Number
NCT04630834
Locations
🇺🇸

Jacobi Medical Center, Bronx, New York, United States

Paracetamol, Dexketoprofen and Ibuprofen In Non-Traumatic Acute Low Back Pain

First Posted Date
2020-10-30
Last Posted Date
2020-10-30
Lead Sponsor
Pamukkale University
Target Recruit Count
210
Registration Number
NCT04609254
Locations
🇹🇷

Pamukkale University, Denizli, Turkey

Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries

First Posted Date
2020-08-21
Last Posted Date
2024-10-26
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
200
Registration Number
NCT04523623

The Effect of Ibuprofen on Women With PCOS.

First Posted Date
2020-07-24
Last Posted Date
2020-07-24
Lead Sponsor
Poznan University of Medical Sciences
Target Recruit Count
20
Registration Number
NCT04485403
Locations
🇵🇱

Division of Infertility and Reproductive Endocrinology, Department of Gynecology and Obsterics, Poznań, Wielkopolskie, Poland

Ibuprofen as a Pain Management in Pediatric Dentistry

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-07-17
Last Posted Date
2020-07-17
Lead Sponsor
Princess Nourah Bint Abdulrahman University
Target Recruit Count
56
Registration Number
NCT04476069
Locations
🇸🇦

College of Dentistry /Princess Nourah Bint Abdulrhman University, Riyadh, Saudi Arabia

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours in the Management of Postoperative Pain.

First Posted Date
2020-06-12
Last Posted Date
2020-06-19
Lead Sponsor
Yi Feng, MD
Target Recruit Count
396
Registration Number
NCT04429282
Locations
🇨🇳

Peking University People's Hospital, Beijing, Beijing, China

Mental Effects of Analgesic Drugs: Paracetamol and Ibuprofen

First Posted Date
2020-06-11
Last Posted Date
2020-06-11
Lead Sponsor
Prof. Jürgen Brockmöller
Target Recruit Count
150
Registration Number
NCT04424420
Locations
🇩🇪

Universitätsmedizin Göttingen, Göttingen, Niedersachsen, Germany

Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Children With PDA

First Posted Date
2020-05-21
Last Posted Date
2020-05-21
Lead Sponsor
Shandong University
Target Recruit Count
500
Registration Number
NCT04397913
Locations
🇨🇳

West China Second University Hospital, Chengdu, Sichuan, China

Intravenous Paracetamol, Dexketoprofen and Ibuprofen in the Treatment of Acute Migraine Attack Headache

First Posted Date
2020-05-04
Last Posted Date
2020-10-27
Lead Sponsor
Pamukkale University
Target Recruit Count
210
Registration Number
NCT04372264
Locations
🇹🇷

Pamukkale University, Denizli, Turkey

Canadian National PDA Treatment Study

First Posted Date
2020-04-15
Last Posted Date
2024-06-21
Lead Sponsor
IWK Health Centre
Target Recruit Count
1663
Registration Number
NCT04347720
Locations
🇨🇦

Royal Alexandra Hospital, Edmonton, Alberta, Canada

🇨🇦

Regina General Hospital, Regina, Saskatchewan, Canada

🇨🇦

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

and more 19 locations
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