Clevidipine
- Generic Name
- Clevidipine
- Brand Names
- Cleviprex
- Drug Type
- Small Molecule
- Chemical Formula
- C21H23Cl2NO6
- CAS Number
- 167221-71-8
- Unique Ingredient Identifier
- 19O2GP3B7Q
- Background
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
- Indication
For the reduction of blood pressure when when oral antihypertensive therapy is not feasible or not desirable.
- Associated Conditions
- Hypertension
Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
- Conditions
- HypertensionHeart Failure
- Interventions
- Drug: Standard of Care IV antihypertensive
- First Posted Date
- 2008-12-05
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 117
- Registration Number
- NCT00803634
- Locations
- 🇺🇸
The Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸Jackson Hospital, Montgomery, Alabama, United States
🇺🇸Louisiana State University Health Sciences Center, Baton Rouge, Louisiana, United States
Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)
- First Posted Date
- 2008-12-01
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 30
- Registration Number
- NCT00799604
- Locations
- 🇺🇸
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States
🇺🇸Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
- First Posted Date
- 2008-04-24
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 37
- Registration Number
- NCT00666328
- Locations
- 🇺🇸
Maine Medical Center, Portland, Massachusetts, United States
🇺🇸Henry Ford Hospital, Detroit, Michigan, United States
🇩🇪Universitatsklinikum Heidelberg, Heidelberg, Germany
Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY)
- First Posted Date
- 2006-08-29
- Last Posted Date
- 2014-05-22
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 131
- Registration Number
- NCT00369837
- Locations
- 🇺🇸
Pennsylvania Hospital, Philadelphia, Pennsylvania, United States
🇺🇸Good Samaritan Hospital, Baltimore, Maryland, United States
🇺🇸Providence Heart & Vascular Institute, d/b/a Providence St. Vincent Medical Center, Portland, Oregon, United States
Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 739
- Registration Number
- NCT00093925
- Locations
- 🇺🇸
Mobile Infirmary Medical Center, Mobile, Alabama, United States
🇺🇸Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸Ochsner Clinic Foundation, New Orleans, Louisiana, United States
Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 629
- Registration Number
- NCT00093886
- Locations
- 🇺🇸
Sacred Heart Health System, Pensacola, Florida, United States
🇺🇸New York University Medical Center, New York, New York, United States
🇺🇸Baptist Medical Center, South, Montgomery, Alabama, United States
Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP)
- First Posted Date
- 2004-10-08
- Last Posted Date
- 2014-05-06
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 739
- Registration Number
- NCT00093912
- Locations
- 🇺🇸
International Heart Institute/St. Patrick Hospital, Missoula, Montana, United States
🇺🇸Mt. Sinai Medical Center, New York, New York, United States
🇺🇸Jackson-Madison County General Hospital, Jackson, Tennessee, United States
Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2)
- First Posted Date
- 2004-10-07
- Last Posted Date
- 2014-05-08
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 206
- Registration Number
- NCT00093262
- Locations
- 🇺🇸
Keck School of Medicine, University of Southern California, Los Angeles, California, United States
🇺🇸Emory Hospital, Atlanta, Georgia, United States
🇺🇸International Heart Institute, Missoula, Montana, United States
Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)
- First Posted Date
- 2004-10-07
- Last Posted Date
- 2014-08-22
- Lead Sponsor
- The Medicines Company
- Target Recruit Count
- 105
- Registration Number
- NCT00093249
- Locations
- 🇺🇸
Cardio-Thoracic Surgeons, PC, Birmingham, Alabama, United States
🇺🇸St Vincent Medical Center, Los Angeles, California, United States
🇺🇸Memorial Herman Memorial City Hospital, Houston, Texas, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.