Clevidipine

Generic Name
Clevidipine
Brand Names
Cleviprex
Drug Type
Small Molecule
Chemical Formula
C21H23Cl2NO6
CAS Number
167221-71-8
Unique Ingredient Identifier
19O2GP3B7Q
Background

Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.

Indication

For the reduction of blood pressure when when oral antihypertensive therapy is not feasible or not desirable.

Associated Conditions
Hypertension
Associated Therapies
-
Clinical Trials
Related News

Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG)

Phase 3
Completed
Conditions
Hypertension
Interventions
Drug: clevidipine
Drug: nitroglycerin
First Posted Date
2004-10-08
Last Posted Date
2014-05-06
Lead Sponsor
The Medicines Company
Target Recruit Count
629
Registration Number
NCT00093886
Locations
🇺🇸

Sacred Heart Health System, Pensacola, Florida, United States

🇺🇸

New York University Medical Center, New York, New York, United States

🇺🇸

Baptist Medical Center, South, Montgomery, Alabama, United States

and more 25 locations

Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2)

Phase 3
Completed
Conditions
Hypertension
Interventions
Drug: placebo
Drug: clevidipine
First Posted Date
2004-10-07
Last Posted Date
2014-05-08
Lead Sponsor
The Medicines Company
Target Recruit Count
206
Registration Number
NCT00093262
Locations
🇺🇸

Keck School of Medicine, University of Southern California, Los Angeles, California, United States

🇺🇸

Emory Hospital, Atlanta, Georgia, United States

🇺🇸

International Heart Institute, Missoula, Montana, United States

and more 12 locations

Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)

Phase 3
Completed
Conditions
Hypertension
Interventions
Drug: placebo
Drug: clevidipine
First Posted Date
2004-10-07
Last Posted Date
2014-08-22
Lead Sponsor
The Medicines Company
Target Recruit Count
105
Registration Number
NCT00093249
Locations
🇺🇸

Cardio-Thoracic Surgeons, PC, Birmingham, Alabama, United States

🇺🇸

St Vincent Medical Center, Los Angeles, California, United States

🇺🇸

Memorial Herman Memorial City Hospital, Houston, Texas, United States

and more 9 locations
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