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Sprifermin

Generic Name
Sprifermin
Drug Type
Biotech
CAS Number
890058-52-3
Unique Ingredient Identifier
UEJ4E476ZP
Background

Sprifermin has been used in trials studying the treatment of Osteoarthritis, Knee and Cartilage Injury of Knee.

A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee

Phase 2
Completed
Conditions
Osteoarthritis, Knee
Interventions
Drug: Placebo
First Posted Date
2013-08-08
Last Posted Date
2020-07-13
Lead Sponsor
EMD Serono Research & Development Institute, Inc.
Target Recruit Count
549
Registration Number
NCT01919164
Locations
🇷🇴

Research site, Bucharest, Romania

🇭🇰

Research Site, Hong Kong, Hong Kong

A Multicenter Trial of Sprifermin (AS902330 [Recombinant Human Fibroblast Growth Factor-18]) or Placebo After Microfracture Surgery for Cartilage Injury of the Knee

Phase 2
Terminated
Conditions
Cartilage Injury of Knee
Interventions
First Posted Date
2012-09-21
Last Posted Date
2017-01-13
Lead Sponsor
EMD Serono
Target Recruit Count
1
Registration Number
NCT01689337

Sprifermin (AS902330) in Cartilage Injury Repair (CIR)

Phase 2
Terminated
Conditions
Isolated Cartilage Injury of the Knee
Interventions
First Posted Date
2010-02-10
Last Posted Date
2016-03-23
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
74
Registration Number
NCT01066871
Locations
🇩🇪

Please contact the Merck KGaA Communication Center, Darmstadt, Germany

Study of AS902330 (rhFGF-18) Administered Intra-articularly in Patients With Knee Primary Osteoarthritis Who Are Candidates for Total Knee Replacement

Phase 1
Completed
Conditions
Knee Osteoarthritis
Interventions
Drug: Placebo
First Posted Date
2009-06-02
Last Posted Date
2014-08-05
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
73
Registration Number
NCT00911469
Locations
🇸🇪

Hässleholms Sjukhus, Hässleholm, Sweden

🇸🇪

Malmö University Hospital, Malmö, Sweden

🇬🇧

Cambridge University Hospitals, Cambridge, United Kingdom

and more 16 locations
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