Nevirapine
- Generic Name
- Nevirapine
- Brand Names
- Viramune
- Drug Type
- Small Molecule
- Chemical Formula
- C15H14N4O
- CAS Number
- 129618-40-2
- Unique Ingredient Identifier
- 99DK7FVK1H
- Background
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
- Indication
For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection.
- Associated Conditions
- Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- -
Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-11-02
- Target Recruit Count
- 76
- Registration Number
- NCT00016601
- Locations
- 🇺🇸
Univ of North Carolina, Chapel Hill, North Carolina, United States
🇺🇸Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States
🇺🇸Indiana Univ Hosp, Indianapolis, Indiana, United States
Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2012-05-21
- Target Recruit Count
- 1125
- Registration Number
- NCT00013520
- Locations
- 🇺🇸
The Ponce de Leon Ctr. CRS, Atlanta, Georgia, United States
🇺🇸Northwestern University CRS, Chicago, Illinois, United States
🇺🇸St. Louis ConnectCare, Infectious Diseases Clinic, St. Louis, Missouri, United States
Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 300
- Registration Number
- NCT00001045
- Locations
- 🇺🇸
St Paul Ramsey Med Ctr, Saint Paul, Minnesota, United States
🇺🇸Adirondack Med Ctr at Saranac Lake, Albany, New York, United States
🇺🇸Mid - Hudson Care Ctr, Albany, New York, United States
Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 440
- Registration Number
- NCT00017719
- Locations
- 🇺🇸
Harbor - UCLA Med. Ctr. - Dept. of Peds., Div. of Infectious Diseases, Torrance, California, United States
🇺🇸WNE Maternal Pediatric Adolescent AIDS CRS, Worcester, Massachusetts, United States
🇺🇸Mt. Sinai Hosp. Med. Ctr. - Chicago, Womens & Childrens HIV Program, Chicago, Illinois, United States
A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children With Prior Treatment
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 217
- Registration Number
- NCT00000902
- Locations
- 🇺🇸
Connecticut Children's Med Ctr, Farmington, Connecticut, United States
🇺🇸Cedars Sinai / UCLA Med Ctr, Los Angeles, California, United States
🇺🇸Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, United States
Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV Drugs
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-04
- Target Recruit Count
- 240
- Registration Number
- NCT00001083
- Locations
- 🇺🇸
Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles, California, United States
🇺🇸Univ of Miami (Pediatric), Miami, Florida, United States
🇺🇸North Shore Univ Hosp, Great Neck, New York, United States
A Study of the Safety and Effectiveness of Treating Advanced AIDS Patients Between Ages 4 and 22 With 7 Drugs, Some at Higher Than Usual Doses
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 6
- Registration Number
- NCT00001108
- Locations
- 🇺🇸
Cook County Hosp, Chicago, Illinois, United States
🇺🇸Univ of Massachusetts Med School, Worcester, Massachusetts, United States
🇺🇸Univ of Mississippi Med Ctr, Jackson, Mississippi, United States
A Pilot Pharmacokinetic Phase I Evaluation of BI-RG-587 in HIV-Infected Children
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2011-03-01
- Target Recruit Count
- 6
- Registration Number
- NCT00000634
- Locations
- 🇺🇸
Univ of Massachusetts Med Ctr / Biotech II, Worcester, Massachusetts, United States
A Study of Nevirapine Used Alone or in Combination With AZT in HIV-1-Infected Children
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2011-03-01
- Target Recruit Count
- 35
- Registration Number
- NCT00001111
- Locations
- 🇺🇸
UCLA Med Ctr / Pediatrics, Los Angeles, California, United States
🇺🇸Univ of Miami (Pediatric), Miami, Florida, United States
🇺🇸Univ of Massachusetts Med Ctr / Biotech II, Worcester, Massachusetts, United States
An Open-Label, Pilot Study to Evaluate the Development of Resistance to Nevirapine (BI-RG-587) in HIV-Infected Patients With CD4 Cell Count >= 500/mm3
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2011-03-01
- Target Recruit Count
- 10
- Registration Number
- NCT00000747
- Locations
- 🇺🇸
UCSD, San Diego, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.