MedPath

Sarpogrelate

Generic Name
Sarpogrelate
Drug Type
Small Molecule
Chemical Formula
C24H31NO6
CAS Number
125926-17-2
Unique Ingredient Identifier
19P708E787
Background

Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.

Indication

用于改善慢性动脉闭塞症所引起的溃疡、疼痛及冷感等缺血性症状。

Clinical Trial to Evaluate Efficacy and Safety of DP-R202 and Anplag in Patients With Artery Occlusive Disease

Phase 3
Completed
Conditions
Peripheral Arterial Disease
Interventions
First Posted Date
2015-03-19
Last Posted Date
2016-11-01
Lead Sponsor
Alvogen Korea
Target Recruit Count
151
Registration Number
NCT02393612

Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study

Phase 3
Completed
Conditions
Diabetes Mellitus
Renal Insufficiency, Chronic
Coronary Artery Disease
Interventions
Drug: Placebo (for Sarpogrelate)
First Posted Date
2014-11-19
Last Posted Date
2014-11-25
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
220
Registration Number
NCT02294643
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam, Korea, Republic of

Sarpogrelate Drug Interaction

Phase 1
Completed
Conditions
Hypertension
Peripheral Artery Disease
Interventions
First Posted Date
2014-03-27
Last Posted Date
2015-02-25
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
9
Registration Number
NCT02097511
Locations
🇰🇷

Ajou University School of Medicine, Suwon, Gyeonggi, Korea, Republic of

Pharmacokinetics and Food Effect of Sarpogrelate HCl CR Formulation in Comparison to Immediate-release Formulation

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: UI03SPG300CT
First Posted Date
2013-04-26
Last Posted Date
2013-04-26
Lead Sponsor
Korea United Pharm. Inc.
Target Recruit Count
50
Registration Number
NCT01841086

The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm

Phase 4
Conditions
Variant Angina
Interventions
First Posted Date
2012-08-29
Last Posted Date
2018-02-09
Lead Sponsor
Samsung Medical Center
Target Recruit Count
200
Registration Number
NCT01674686
Locations
🇰🇷

Hyoen-Cheol Gwon, MD,PhD, Seoul, Korea, Republic of

Impact of Sarpogrelate in the Function of Endothelial Progenitor Cells

Not Applicable
Conditions
Atherosclerosis
First Posted Date
2012-03-08
Last Posted Date
2012-03-08
Lead Sponsor
Aichi Gakuin University
Target Recruit Count
20
Registration Number
NCT01548274
Locations
🇯🇵

Aichi-Gakuin University, Nagoya, Aichi, Japan

Pharmacokinetic / Pharmacodynamic (PK/PD) Study of Multiple Doses of DP-R202 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2011-09-07
Last Posted Date
2011-09-07
Lead Sponsor
Alvogen Korea
Target Recruit Count
36
Registration Number
NCT01429688
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

Safety and Pharmacokinetic Characteristics of DP-R202 in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2011-08-23
Last Posted Date
2011-08-23
Lead Sponsor
Alvogen Korea
Target Recruit Count
36
Registration Number
NCT01421563
Locations
🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

The Prevention of Contrast Induced Nephropathy by Sarpogrelate in Patients With Chronic Kidney Disease

Phase 4
Conditions
Chronic Kidney Disease
Interventions
First Posted Date
2010-07-20
Last Posted Date
2010-07-20
Lead Sponsor
Seoul National University Boramae Hospital
Target Recruit Count
212
Registration Number
NCT01165567
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

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