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TAS-117

Generic Name
TAS-117
Drug Type
Small Molecule
Chemical Formula
C26H24N4O2
CAS Number
1402602-94-1
Unique Ingredient Identifier
QI52W1ZIIB
Background

TAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).

TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

Phase 1
Terminated
Conditions
Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations
Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations
Interventions
First Posted Date
2021-02-25
Last Posted Date
2024-06-27
Lead Sponsor
Taiho Oncology, Inc.
Target Recruit Count
17
Registration Number
NCT04770246
Locations
🇺🇸

Sarcoma Oncology Research Center, Santa Monica, California, United States

🇺🇸

Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 5 locations

K-BASKET, TAS-117, PI3K/AKT Gene Aberration

Phase 2
Completed
Conditions
Solid Tumor, Adult
Interventions
First Posted Date
2017-01-11
Last Posted Date
2021-04-22
Lead Sponsor
Yonsei University
Target Recruit Count
13
Registration Number
NCT03017521
Locations
🇰🇷

Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of

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