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Monalizumab

Generic Name
Monalizumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1228763-95-8
Unique Ingredient Identifier
3ZXZ2V0588
Background

Monalizumab has been used in trials studying the treatment of Gynecologic Cancer, Chronic Lymphocytic Leukemia, and Squamous Cell Carcinoma of the Oral Cavity.

Associated Conditions
-
Associated Therapies
-

Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial

Phase 1
Active, not recruiting
Conditions
Locally Advanced Lung Non-Small Cell Carcinoma
Locally Recurrent Lung Non-Small Cell Carcinoma
Unresectable Lung Non-Small Cell Carcinoma
Stage II Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Interventions
Radiation: Accelerated Hypofractionated Radiation Therapy
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Biological: Durvalumab
Procedure: Magnetic Resonance Imaging of the Brain with and without Contrast
Biological: Monalizumab
Biological: Oleclumab
Radiation: Radiation Therapy
First Posted Date
2019-01-14
Last Posted Date
2024-12-16
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
48
Registration Number
NCT03801902
Locations
🇺🇸

MD Anderson in The Woodlands, Conroe, Texas, United States

🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

🇺🇸

MD Anderson West Houston, Houston, Texas, United States

and more 53 locations
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