BMS-986519
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Conditions
- Alzheimer's Disease
- Interventions
- First Posted Date
- 2025-05-16
- Last Posted Date
- 2025-05-16
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 586
- Registration Number
- NCT06976216
- Locations
- ðŸ‡ðŸ‡·
Local Institution - 0216, Osijek, Croatia
ðŸ‡ðŸ‡·Local Institution - 0267, Rijeka, Croatia
ðŸ‡ðŸ‡·Local Institution - 0240, Zagreb, Croatia
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Conditions
- Alzheimer's Disease
- Interventions
- First Posted Date
- 2025-05-16
- Last Posted Date
- 2025-05-16
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 586
- Registration Number
- NCT06976203
- Locations
- 🇫🇮
Local Institution - 0022, Oulu, Pohjois-Pohjanmaa, Finland
🇫🇮Local Institution - 0009, Turku, Varsinais-Suomi, Finland
🇫🇮Local Institution - 0008, Kuopio, Finland
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
- Conditions
- Alzheimer DiseasePsychosis
- Interventions
- First Posted Date
- 2025-04-27
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 1046
- Registration Number
- NCT06947941
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
- First Posted Date
- 2025-04-22
- Last Posted Date
- 2025-05-18
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 600
- Registration Number
- NCT06937229
- Locations
- 🇺🇸
Local Institution - 2609, Chandler, Arizona, United States
🇺🇸Local Institution - 2620, Canoga Park, California, United States
🇺🇸Local Institution - 2614, San Diego, California, United States
Safety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric Disorders
- First Posted Date
- 2025-02-28
- Last Posted Date
- 2025-05-14
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 36
- Registration Number
- NCT06853171
- Locations
- 🇺🇸
Pillar Clinical Research- Little Rock, Little Rock, Arkansas, United States
🇺🇸NRC Research Institute, Orange, California, United States
🇺🇸CenExel iResearch, LLC, Decatur, Georgia, United States
A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Xanomeline With Trospium Chloride Versus KarXT in Healthy Adult and Elderly Participants of Japanese Ethnicity and to Assess the Effect of Omeprazole on the PK of Xanomeline With Trospium Chloride in Healthy Adult Participants
- Conditions
- Healthy Volunteers
- Interventions
- First Posted Date
- 2024-09-20
- Last Posted Date
- 2025-05-15
- Lead Sponsor
- Karuna Therapeutics
- Target Recruit Count
- 78
- Registration Number
- NCT06605950
- Locations
- 🇺🇸
Cenexel ACT (Anaheim Clinical Trials), Anaheim, California, United States
🇺🇸Local Institution - 0002, Anaheim, California, United States
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