Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI
Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivi...

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in comb...

Associated Conditions
Bipolar 1 Disorder, Depressive Episodes, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Mixed manic depressive episode, Post Traumatic Stress Disorder (PTSD), Psychosis, Schizophrenia, Acute Manic episode
Associated Therapies
-

Interaction Between Cocaine and Quetiapine - 1

Phase 1
Conditions
First Posted Date
2004-07-16
Last Posted Date
2017-01-11
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
12
Registration Number
NCT00087750
Locations
🇺🇸

Boston University Medical Center, Boston, Massachusetts, United States

Treatment and Outcome of Early Onset Bipolar Disorder

Phase 4
Completed
Conditions
First Posted Date
2002-11-13
Last Posted Date
2014-01-22
Lead Sponsor
Northwell Health
Target Recruit Count
40
Registration Number
NCT00048802
Locations
🇺🇸

The Zucker Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, New York, United States

Switching Medication to Treat Schizophrenia

First Posted Date
2002-09-05
Last Posted Date
2016-04-28
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
219
Registration Number
NCT00044655

Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)

Phase 4
Completed
Conditions
First Posted Date
2002-08-15
Last Posted Date
2009-12-11
Lead Sponsor
National Institute on Aging (NIA)
Target Recruit Count
60
Registration Number
NCT00043849
Locations
🇺🇸

Fletcher Allan Health Care, Inc., Burlington, Vermont, United States

🇺🇸

Memory Clinic at Southwestern Vermont Medical Center, Bennington, Vermont, United States

🇺🇸

University of Pittsburgh, Alzheimer's Disease Research Center, Pittsburgh, Pennsylvania, United States

and more 18 locations

Antipsychotic Response in Schizophrenia

Phase 4
Completed
Conditions
First Posted Date
2001-07-05
Last Posted Date
2009-01-21
Lead Sponsor
US Department of Veterans Affairs
Registration Number
NCT00018668
Locations
🇺🇸

Department of Veterans Affairs, San Diego, California, United States

Quetiapine vs Haloperidol Decanoate for the Long Term Treatment of Schizophrenia and Schizoaffective Disorder

Not Applicable
Completed
Conditions
First Posted Date
2001-07-05
Last Posted Date
2009-01-21
Lead Sponsor
US Department of Veterans Affairs
Registration Number
NCT00018642
Locations
🇺🇸

VA Greater Los Angeles Healthcare System, Los Angeles, California, United States

CATIE-Alzheimer's Disease Trial

Not Applicable
Completed
Conditions
First Posted Date
2001-04-23
Last Posted Date
2015-06-17
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
450
Registration Number
NCT00015548
Locations
🇺🇸

VA Medical Center, Coatesville, Pennsylvania, United States

🇺🇸

University of California, Irvine Medical Center, Irvine, California, United States

🇺🇸

Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States

and more 31 locations

CATIE- Schizophrenia Trial

Phase 4
Completed
Conditions
First Posted Date
2001-04-09
Last Posted Date
2015-06-17
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
1600
Registration Number
NCT00014001
Locations
🇺🇸

Staten Island University Hospital, Staten Island, New York, United States

🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

🇺🇸

Northwestern Medical School Department of Psychiatry, Chicago, Illinois, United States

and more 51 locations
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