MedPath

Quetiapine

Generic Name
Quetiapine
Brand Names
Seroquel
Drug Type
Small Molecule
Chemical Formula
C21H25N3O2S
CAS Number
111974-69-7
Unique Ingredient Identifier
BGL0JSY5SI

Overview

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as Clozapine and Olanzapine.

Background

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as Clozapine and Olanzapine.

Indication

Quetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may be used to manage depressive episodes in bipolar disorder. In addition to the above indications, quetiapine is used in combination with antidepressant drugs for the treatment of major depression. Some off-label uses for this drug include the management of post-traumatic stress disorder (PTSD), generalized anxiety disorder, and psychosis associated with Parkinson's disease.

Associated Conditions

  • Bipolar 1 Disorder
  • Depressive Episodes
  • Generalized Anxiety Disorder
  • Major Depressive Disorder (MDD)
  • Mixed manic depressive episode
  • Post Traumatic Stress Disorder (PTSD)
  • Psychosis
  • Schizophrenia
  • Acute Manic episode

FDA Approved Products

Quetiapine Fumarate
Manufacturer:Ingenus Pharmaceuticals, LLC
Route:ORAL
Strength:50 mg in 1 1
Approved: 2022/08/15
NDC:50742-635
Quetiapine Fumarate
Manufacturer:Ingenus Pharmaceuticals, LLC
Route:ORAL
Strength:400 mg in 1 1
Approved: 2022/08/15
NDC:50742-639
Quetiapine Fumarate
Manufacturer:Ingenus Pharmaceuticals, LLC
Route:ORAL
Strength:300 mg in 1 1
Approved: 2022/08/15
NDC:50742-638
Quetiapine Fumarate
Manufacturer:REMEDYREPACK INC.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2024/04/02
NDC:70518-3877
Quetiapine
Manufacturer:Accord Healthcare Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/12/12
NDC:16729-146

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath